Hostname: page-component-cd9895bd7-p9bg8 Total loading time: 0 Render date: 2024-12-18T07:01:01.309Z Has data issue: false hasContentIssue false
  • English
  • Français

Study of ethmoid sinus involvement in multibacillary leprosy

Published online by Cambridge University Press:  29 June 2007

S. Srinivasan ,
V. I. Nehru ,
S. B. S. Mann ,
V. K. Sharma ,
J. R. Bapuraj  and
A. Das
S. Srinivasan
Affiliation:
Department of Otorhinolaryngology, Head and Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh – 160 012, India
V. I. Nehru*
Affiliation:
Department of Otorhinolaryngology, Head and Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh – 160 012, India
S. B. S. Mann
Affiliation:
Department of Otorhinolaryngology, Head and Neck Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh – 160 012, India
V. K. Sharma
Affiliation:
Department of Dermatology, Postgraduate Institute of Medical Education and Research, Chandigarh – 160 012, India
J. R. Bapuraj
Affiliation:
Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh – 160 012, India
A. Das
Affiliation:
Department of Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh – 160 012, India
*
Address for correspondence: Dr. Vikas I. Nehru, Assistant Professor, Department of Otolaryngology, PGIMER, Chandigarh 160 012, India. Fax: 91-172-540401
Get access Rights & Permissions [Opens in a new window]

Abstract

The nasal mucosal involvement in lepromatous leprosy is well recognized. Currently interest has centred around the involvement of paranasal sinuses in leprosy. They act as a reservoir and constant source of reinfection to the nasal mucosa. In the present prospective study 25 untreated patients with multi-bacillary leprosy were included. Clinical examination, computed tomography (CT) scan of paranasal sinuses, ethmoid sinus endoscopy and biopsy were carried out in all patients, to investigate the involvement of the paranasal sinuses in leprosy.

Ethmoid sinus involvement was noted in 20 patients on CT scan. Bilateral involvement was more common (65 per cent). Anterior ethmoids were more commonly affected (65 per cent). On ethmoid sinus endoscopy abnormal mucosa was noted in 17 patients (68 per cent). Ethmoid sinus biopsy was confirmative in 16 patients (64 per cent). Statistically significant correlation was found between CT findings, sinus endoscopy and sinus biopsy findings.

Keywords

Ethinoid sinusLeprosy, lepromatousLeprosy, borderline
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 112 , Issue 11 , November 1998 , pp. 1038 - 1041
Copyright
Copyright © JLO (1984) Limited 1998

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Barton, R. P. E. (1974) A clinical study of the nose in lepromatous leprosy. Leprosy Review 45: 135–144.CrossRefGoogle ScholarPubMed
Barton, R. P. E. (1979) Radiological changes in the paranasal sinuses in lepromatous leprosy. Journal of Laryngology and Otology 93: 597–600.CrossRefGoogle ScholarPubMed
Chacko, C. J. G., Bhanu, T., Victor, V., Alexander, R., Taylor, P. M., Job, C. K. (1979) The significance of changes in the nasal mucosa in intermediate, tuberculoid and borderline leprosy. Leprosy in India 51: 8–22.Google Scholar
Davey, T. F. (1974) The nose in leprosy: steps to the better understanding. Leprosy Review 45: 97–103.CrossRefGoogle Scholar
Hauhnar, C. Z., Mann, S. B. S., Sharma, V. K., Kaur, S., Mehta, S., Radotra, B. D. (1992) Maxillary antrum involvement in multibacillary leprosy. A radiologic, sinuscopic and histologic assessment. International Journal of Leprosy 60: 390–395.Google ScholarPubMed
McDougall, A. C., Weddell, A. G. M., Reis, R. J. W. (1975) Lepromatous leprosy in nose after one year of dapsone treatment: Histopathological findings. Leprosy Review 46: 277–279.CrossRefGoogle ScholarPubMed
Ridley, D. S., Jopling, W. H. (1966) Classification of leprosy according to inununity: a five group system. International Journal of Leprosy 34: 255–273.Google ScholarPubMed
Soni, N. K. (1988) Radiological study of the paranasal sinuses in lepromatous leprosy. Indian Journal of Leprosy 60: 285–289.Google ScholarPubMed
Soni, N. K. (1989) Antroscopic study of the maxillary antrum in lepromatous leprosy. Journal of Laryngology and Otology 103: 502–503.CrossRefGoogle ScholarPubMed