Hostname: page-component-cd9895bd7-dzt6s Total loading time: 0 Render date: 2024-12-27T11:29:27.487Z Has data issue: false hasContentIssue false
  • English
  • Français

Stridor: unusual presentation of multiple myeloma

Published online by Cambridge University Press:  08 March 2006

David Sinclair ,
Adel Resouly  and
Anne Spedding
David Sinclair
Affiliation:
Department of Clinical Biochemistry, Queen Alexandra Hospital, Portsmouth, UK.
Adel Resouly
Affiliation:
Department of Clinical Biochemistry, Head and Neck Unit, Queen Alexandra Hospital, Portsmouth, UK.
Anne Spedding
Affiliation:
Department of Histopathology, Queen Alexandra Hospital, Portsmouth, UK.
Get access Rights & Permissions [Opens in a new window]

Abstract

We present a patient with multiple myeloma whose only presenting symptom was stridor caused by a subglottic stenosis. Biopsy suggested the presence of amyloid which prompted immunological investigations that showed hypogammaglobulinaemia and the presence of Bence Jones proteinuria at 0.93 g/24 hours. Further investigation demonstrated a 15 per cent plasma cell infiltrate into the bone marrow and a lytic lesion in the mid-shaft of the right femur. Chemotherapy and localized radiotherapy were commenced. This is a most unusual presentation of multiple myeloma and shows that immunoglobulin profiles should be properly investigated in such cases.

Keywords

Respiratory SoundsMultiple MyelomaBence Jones Protein
Type
Other
Information
The Journal of Laryngology & Otology , Volume 117 , Issue 10 , October 2003 , pp. 829 - 831
Copyright
© Royal Society of Medicine Press Limited 2003

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)