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Solitary fibrous tumour of the tongue: a series of four cases

Published online by Cambridge University Press:  07 July 2017

M M Dungarwalla ,
A W Barrett  and
A Gulati
M M Dungarwalla*
Affiliation:
Department of Oral and Maxillofacial Surgery, Queen Victoria Hospital NHS Foundation Trust, East Grinstead, UK
A W Barrett
Affiliation:
Department of Histopathology, Queen Victoria Hospital NHS Foundation Trust, East Grinstead, UK
A Gulati
Affiliation:
Department of Oral and Maxillofacial Surgery, Queen Victoria Hospital NHS Foundation Trust, East Grinstead, UK
*
Address for correspondence: Mr Mohammed M Dungarwalla, Department of Oral and Maxillofacial Surgery, Queen Victoria Hospital NHS Foundation Trust, East Grinstead RH19 3DZ, UK E-mail: [email protected]
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Abstract

Background:

Solitary fibrous tumour is a soft tissue tumour of mesenchymal origin. It was first described in the pleura and has since been reported in many anatomical locations. Thirteen cases in the tongue have hitherto been reported. A positive CD34 result has traditionally been used to confirm the diagnosis, although this is often non-specific to solitary fibrous tumour. To date, nuclear STAT6 expression has not been reported in solitary fibrous tumour of the tongue.

Method:

This paper presents a further four cases of solitary fibrous tumour of the tongue, the largest series to date. Clinical, histopathological and immunohistochemical findings are detailed, including nuclear STAT6 expression.

Results:

All four cases were positive for CD34; two cases showed nuclear expression of STAT6. The tumours were excised completely and there have been no recurrences in at least one year.

Conclusion:

Solitary fibrous tumour should be considered as a differential diagnosis for tongue swellings, with the potential to recur.

Keywords

Solitary Fibrous TumourSignal Transducer And Activator Of Transcription 6CD34 Antigen
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 131 , Issue 9 , September 2017 , pp. 838 - 841
Copyright
Copyright © JLO (1984) Limited 2017 

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