Hostname: page-component-586b7cd67f-l7hp2 Total loading time: 0 Render date: 2024-11-28T04:29:28.291Z Has data issue: false hasContentIssue false
  • English
  • Français

Solitary fibrous tumour of the tongue: a series of four cases

Published online by Cambridge University Press:  07 July 2017

M M Dungarwalla ,
A W Barrett  and
A Gulati
M M Dungarwalla*
Affiliation:
Department of Oral and Maxillofacial Surgery, Queen Victoria Hospital NHS Foundation Trust, East Grinstead, UK
A W Barrett
Affiliation:
Department of Histopathology, Queen Victoria Hospital NHS Foundation Trust, East Grinstead, UK
A Gulati
Affiliation:
Department of Oral and Maxillofacial Surgery, Queen Victoria Hospital NHS Foundation Trust, East Grinstead, UK
*
Address for correspondence: Mr Mohammed M Dungarwalla, Department of Oral and Maxillofacial Surgery, Queen Victoria Hospital NHS Foundation Trust, East Grinstead RH19 3DZ, UK E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Background:

Solitary fibrous tumour is a soft tissue tumour of mesenchymal origin. It was first described in the pleura and has since been reported in many anatomical locations. Thirteen cases in the tongue have hitherto been reported. A positive CD34 result has traditionally been used to confirm the diagnosis, although this is often non-specific to solitary fibrous tumour. To date, nuclear STAT6 expression has not been reported in solitary fibrous tumour of the tongue.

Method:

This paper presents a further four cases of solitary fibrous tumour of the tongue, the largest series to date. Clinical, histopathological and immunohistochemical findings are detailed, including nuclear STAT6 expression.

Results:

All four cases were positive for CD34; two cases showed nuclear expression of STAT6. The tumours were excised completely and there have been no recurrences in at least one year.

Conclusion:

Solitary fibrous tumour should be considered as a differential diagnosis for tongue swellings, with the potential to recur.

Keywords

Solitary Fibrous TumourSignal Transducer And Activator Of Transcription 6CD34 Antigen
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 131 , Issue 9 , September 2017 , pp. 838 - 841
Copyright
Copyright © JLO (1984) Limited 2017 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1 Klemperer, P, Rabin, C. Primary neoplasms of the pleura. A report of five cases. Am J Ind Med 1992;22:4–31 CrossRefGoogle ScholarPubMed
2 Piattelli, A, Fioroni, M, Rubini, C. Solitary fibrous tumor of the tongue. Oral Oncol 1998;34:431–4CrossRefGoogle Scholar
3 Migita, M, Yoshino, M, Kobayashi, D, Shiomi, S, Enatsu, K, Shigematsu, S et al. A large solitary fibrous tumor of the tongue. J Oral Maxillofac Surg 2012;70:871–4CrossRefGoogle ScholarPubMed
4 Vafiadou, M, Dimitrakopoulos, I, Georgitzikis, I, Hytiroglou, P, Bobos, M, Karakasis, D. Solitary fibrous tumor of the tongue: case report and literature review. Int J Oral Maxillofac Surg 2008;37:1067–9CrossRefGoogle ScholarPubMed
5 Shnayder, Y, Greenfield, B, Oweity, T, DeLacure, M. Malignant solitary fibrous tumor of the tongue. Am J Otolaryngol 2003;24:246–9CrossRefGoogle ScholarPubMed
6 Suster, S, Nascimento, A, Miettinen, M, Sickel, J, Moran, C. Solitary fibrous tumors of soft tissue. Am J Surg Pathol 1995;19:1257–66CrossRefGoogle ScholarPubMed
7 O'Regan, E, Vanguri, V, Allen, CM, Eversole, LR, Wright, JM, Woo, S. Solitary fibrous tumor of the oral cavity: clinicopathologic and immunohistochemical study of 21 cases. Head Neck Pathol 2009;3:106–15CrossRefGoogle ScholarPubMed
8 Guillou, L, Fletcher, JA, Fletcher, CD, Mandahl, M. Extrapleural solitary fibrous tumor and haemangiopericytoma. In: Hogendoorn, PC, Mertens, F, Bridge, J, eds. WHO Classification of Tumors of Soft Tissue and Bone. Lyon: IARC Press, 2013;86–8Google Scholar
9 Fusconi, M, Ciofalo, A, Greco, A, Pulice, G, Macci, M, Mariotti, M et al. Solitary fibrous tumor of the oral cavity: case report and pathologic consideration. J Oral Maxillofac Surg 2008;66:530–4CrossRefGoogle ScholarPubMed
10 Chan, J. Solitary fibrous tumor - everywhere, and a diagnosis in vogue. Histopathology 1997;31:568–76CrossRefGoogle Scholar
11 Yoshida, A, Tsuta, K, Ohno, M, Yoshida, M, Narita, Y, Kawai, A et al. STAT6 immunohistochemistry is helpful in the diagnosis of solitary fibrous tumors. Am J Surg Pathol 2014;38:552–9CrossRefGoogle ScholarPubMed
12 Penel, N, Amela, E, Decanter, G, Robin, Y, Marec-Berard, P. Solitary fibrous tumors and so-called hemangiopericytoma. Sarcoma 2012;2012:1–6 CrossRefGoogle ScholarPubMed
13 Matsuzaki, H, Iwamoto, M, Chiba, T, Saito, S, Yagisawa, J, Ichikawa, H et al. Case of hemangiopericytoma extending from cheek to infratemporal fossa. Shikwa Gakuho 2009;109:206 Google Scholar
14 Abrari, A, Bakshi, V. Solitary fibrous tumor (SFT) of the residual tongue, post partial glossectomy for carcinoma. Indian J Pathol Microbiol 2014;57:648–50CrossRefGoogle ScholarPubMed
15 Jabłońska, J, Jesionek-Kupnicka, D, Kordek, R. Solitary fibrous tumor of the tongue of an adolescent--a case report with immunohistochemical studies. Pol J Pathol 2009;1:57–9Google Scholar
16 Nkenke, E, Fenner, M, Lell, M, Vairaktaris, E, Neukam, F, Faller, G. Solitary fibrous tumor of the tongue [in German]. HNO 2007;55:287–92CrossRefGoogle Scholar
17 Wu, S, Vang, R, Clubb, FJ Jr, Connelly, J. Solitary fibrous tumor of the tongue: report of a case with immunohistochemical and ultrastructural studies. Ann Diagn Pathol 2002;6:168–71CrossRefGoogle ScholarPubMed
18 Vargas, P, Alves, F, Lopes, M, Siqueira, S, Menezes, L, Aldred, V et al. Solitary fibrous tumor of the mouth: report of two cases involving the tongue and cheek. Oral Dis 2002;8:111–15CrossRefGoogle Scholar
19 Yamashita, Y, Satoh, T, Goto, M. Solitary fibrous tumor of the tongue: a case report with immunohistochemical studies. Int J Oral Maxillofac Surg 2002;31:681–3CrossRefGoogle Scholar
20 Han, Y, Zhang, Q, Yu, X, Han, X, Wang, H, Xu, Y et al. Immunohistochemical detection of STAT6, CD34, CD99 and BCL-2 for diagnosing solitary fibrous tumors/hemangiopericytomas. Int J Clin Exp Pathol 2015;8:13166–75Google ScholarPubMed
21 Cox, D, Daniels, T, Jordan, R. Solitary fibrous tumor of the head and neck. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010;110:79–84 CrossRefGoogle ScholarPubMed
22 Künzel, J, Hainz, M, Ziebart, T, Pitz, S, Ihler, F, Strieth, S et al. Head and neck solitary fibrous tumors: a rare and challenging entity. Eur Arch Otorhinolaryngol 2015;273:1589–98CrossRefGoogle ScholarPubMed