Hostname: page-component-78c5997874-lj6df Total loading time: 0 Render date: 2024-11-02T19:59:52.713Z Has data issue: false hasContentIssue false
  • English
  • Français

Serum enzymes in head and neck cancer III

Published online by Cambridge University Press:  29 June 2007

Harbans Lal ,
S. K. Munjal ,
Umesh Wig  and
A. S. Saini
Harbans Lal*
Affiliation:
Department of Biochemistry, Medical College, Rohtak, India.
S. K. Munjal
Affiliation:
Department of ENT, Medical College, Rohtak, India.
Umesh Wig
Affiliation:
Department of ENT, Medical College, Rohtak, India.
A. S. Saini
Affiliation:
Department of Biochemistry, Medical College, Rohtak, India.
*
Dr. Harbans Lai, Department of Biochemistry, 12/9J, Medical College, Rohtak-124001, India.
Get access Rights & Permissions [Opens in a new window]

Abstract

Serum adenosine deaminase (ADA) levels were estimated in a group of 40 patients with head and neck cancer. The mean value was significantly higher in patients compared to controls. The increase was higher in cases of ulcerative growths than of proliferative growths, and activity was increased with advancement in the stage of the cancer. After radiotherapy, a gradual and significant decrease in serum ADA activity was observed.

Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 101 , Issue 10 , October 1987 , pp. 1062 - 1065
Copyright
Copyright © JLO (1984) Limited 1987

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bodansky, O. (1954) Serum phosphohexose iso-merase incancer.II.Asanindexof tumor growth in metastatic carcinoma of the breast. Cancer, 7: 1200–1226.3.0.CO;2-9>CrossRefGoogle Scholar
Bodansky, O. (1955) Serum phosphohexose iso-merase in cancer. III. As an index of tumor growth in metastatic carcinoma of the prostate. Cancer, 8: 1087–1114.Google Scholar
Giusti, G. (1974) Adenosine deaminase. Methods of Enzymatic Analysis, 2: 1092–1099.Google Scholar
Goel, H., Kohli, G. S. and Lai, H. (1986) Serum phosphohexose isomerase levels in patients with head and neck cancer. Journal of Laryngology and Otology 100: 581–585.Google Scholar
Gutman, A. B. (1959) Serum alkaline phosphatase activity in diseases of skeletal and hepatobiliary systems. A consideration of the current status. American Journal of Medicine, 27: 875–901.Google Scholar
Ishii, K. and Green, H. (1973) Lethality and adenosine for cultured mammalian cells by interference with pyrimidine biosynthesis. Journal of Cell Science, 13: 429–439.Google Scholar
Kate, J. T., Wijnen, J. T., Goes, R. G. M. V., Quadt, R., Griffioen, G., Bosmen, F. T. and Khan, P. M. (1984) Quantitative changes in adenosine deaminase isoenzymes in human colorectal ade-nocarcinomas. Cancer Research, 44: 4688–4692.Google Scholar
Koehler, L. H. and Benz, E. J. (1962) Serum adenosine deaminase: Methodology and clinical applications. Clinical Chemistry, 8: 133–140.CrossRefGoogle Scholar
Nishihara, H., Akedo, H., Okada, H. and Haltor, S. (1970) Multienzyme patterns of serum adenosine deaminase by agar gel electrophoresis: an evaluation of the diagnostic value in lung cancer. Clinica Chimica Acta, 30: 251–258.Google Scholar
Raczynska, J., Jonas, S. and Krawczynski, J. (1966) Diagnostic value of adenosine deaminase in some liver diseases. Clinica Chimica Acta, 13: 151–154.CrossRefGoogle Scholar
Sufrin, G., Tritsch, G. L., Mittelman, A. and Murphy, G. P. (1978) Adenosine deaminase activity in patients with carcinoma of the bladder. Journal of Urology, 119: 343–346.CrossRefGoogle Scholar
UICC (1978) Report of Committee on TNM Classification. Geneva.Google Scholar
Vaid, P., Sharma, D. C. and Shastri, K. D. (1974) A clinico-biochemical study of phosphohexose-iso-merase, aliesterase and sulphydryl group in 25 normal and 35 cancer suspects. Indian Journal of Cancer, 11: 448–456.Google Scholar
Wroblewski, F. and LaDue, J. S. (1955) Serum glu-tamic oxaloacetic—transaminase activity as an index of liver-cell injury from cancer. A preliminary report. Cancer, 8: 1155–1163.3.0.CO;2-V>CrossRefGoogle Scholar