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Seroprevalence of Chlamydia pneumoniae infections in otolaryngeal diseases

Published online by Cambridge University Press:  29 June 2007

Kazuhiro Hashiguchi ,
Hiroshi Ogawa  and
Yukumasa Kazuyama
Kazuhiro Hashiguchi*
Affiliation:
ENT Division, Kitasato Institute Hospital, Tokyo.
Hiroshi Ogawa
Affiliation:
ENT Division, Kitasato Institute Hospital, Tokyo.
Yukumasa Kazuyama
Affiliation:
Research and Development Centre of Hygienic Science, Kitasato University.
*
K. Hashiguchi, ENT Division, Kitasato Institute Hospital, 5-9-1, Shirogane, Minato-ku, Tokyo 108, Japan.
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Abstract

We studied the seroprevalence of antibodies to Chlamydia pneumoniae, the third species of chlamydia, in patients with acute infections in otolaryngeal sites. The patients were divided into five diagnostic groups, i.e. sinusitis, otitis media, tonsillitis, laryngitis and bronchitis group. Antibodies were measured by the microimmunofluorescent method. Antibodies confirming past infection with C. pneumoniae were found 46.2 per cent of the patients in the diagnostic groups and 44.7 per cent of the subjects in the control group. The difference between these two groups was not statistically significant. Acute or recent antibodies were detected in 10.5 per cent (2/19) of these patients with sinusitis, 19.2 per cent (10/52) of those with tonsillitis, 23.5 per cent (8/34) of those with otitis media, 18.2 percent (6/33) of those with laryngitis and 22.8 percent (13/57) of those with bronchitis, whereas only one member of the control group had acute antibodies. These data suggested that C. pneumoniae is an important and common pathogen of otolaryngeal disease.

Keywords

Chlamydia infectionsOtolaryngologic diseases
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 106 , Issue 3 , March 1992 , pp. 208 - 210
Copyright
Copyright © JLO (1984) Limited 1992

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References

Dwyer, R. St. C., Treharne, J. D., Jones, B. R., Herring, J. (1972) Chlamydial infection. Results of micro-immunofluorescence tests for the detection of type-specific antibody in certain chlamydial infections. British Journal of Venereal diseases, 48: 452–459.Google ScholarPubMed
Grayston, J. T. (1989) Chlamydia pneumoniae. Strain TWAR. Chest, 95: 664–669.CrossRefGoogle ScholarPubMed
Grayston, J. T., Campbell, L. A., Kuo, C. C, Mordhorst, C. H., Saikku, P., Thorn, D. H., Wang, S. P. (1990) A new respiratory tract pathogen: Chlamydia pneumonia strain TWAR. Journal of Infectious Diseases, 161: 618–625.CrossRefGoogle ScholarPubMed
Grayston, J. T., Kuo, C. C, Campbell, L. A., Wang, S. P. (1989 a) Chlamydia pneumoniae sp. nov. for Chlamydia sp. strain TWAR. International Journal of Systematic Bacteriology, 39: 88–90.CrossRefGoogle Scholar
Grayston, J. T., Kuo, C. C, Wang, S. P., Altaian, J. (1986) A new Chlamydia psittaci strain, TWAR, isolated in acute respiratory tract infections. New England Journal of Medicine, 315: 161–168.CrossRefGoogle ScholarPubMed
Grayston, J. T, Wang, S. P., Kuo, C. C, Campbell, L. A. (1989 b) Current knowledge on Chlamydia pneumoniae, strain TWAR, an important cause of pneumonia and other acute respiratory diseases. European Journal of Clinical Microbiology Infectious Disease, 8: 191–202.CrossRefGoogle ScholarPubMed
Huovinen, P., Lahtonen, R., Ziegler, T., Meurman, O., Hakkarainen, K., Miettinen, A., Arstila, P., Eskola, J., Saikku, P. (1989) Pharyngitis in adults: the presence and coexistence of viruses and bacterial organisms. Annals of Internal Medicine, 110: 612–616.CrossRefGoogle ScholarPubMed
Ogawa, H., Fujisawa, T., Kazuyama, Y. (1990) Isolation of Chlamydia pneumoniae from the middle ear aspirates of otitis media with effusion: Case report. Journal of Infectious Diseases, 162: 1000–1001.CrossRefGoogle ScholarPubMed
Ogawa, H., Hashiguchi, K., Kazuyama, Y., Masuda, H., Yamazaki, Y. (1991) Respiratory tract diseases due to C. pneumoniae. Nippon Jibiinkouka Gakkai Kaiho, 94: 351–356.CrossRefGoogle Scholar
Saikku, P., Wang, S. P., Kleemola, M., Brander, E., Rusanen, E., Grayston, J. T. (1985) An epidemic of mild pneumonia due to an unusual strain of Chlamydia psittaci. Journal of Infectious Diseases, 151: 832–839.CrossRefGoogle Scholar
Thorn, D. H., Grayston, J. T., Wang, S. P., Kuo, C. C, Altman, J. (1990) Chlamydiapneumoniae strain TWAR, Mycoplasmapneumoniae, and viral infections in acute respiratory disease in a university student health clinic population. American Journal of Epidemiology, 132: 248–256.Google Scholar
Wang, S. P., Grayston, J. T. (1970) Immunological relationship between genital TRIC, lymphogranuloma venereum, and related organisms in a new microtitre indirect immunorluorscence test. American Journal of Ophthalmology, 70: 367–374.CrossRefGoogle Scholar
Wang, S. P., Grayston, J. T. (1990) Population prevalence antibody to Chlamydia pneumoniae, strain TWAR. In Chlamydial infections (Bowie, W. R., Coldwell, H. T., Jones, R. P., Mardh, P.-A., Ridgway, G. L., Schachter, J., Stamm, W. E., Ward, M. E., eds.) Cambridge University Press, Cambridge, p. 402–405.Google Scholar