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Second primary cancer of the larynx in patients with lung cancer

Published online by Cambridge University Press:  29 June 2007

Yoav P. Talmi ,
Lev Bedrin ,
Alexander Waller ,
Zeev Horowitz ,
Yair Skurnik ,
Abraham Adunski  and
Jona Kronenberg
Yoav P. Talmi*
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, The Chaim Sheba Medical Center and the Tel-Aviv University Sackler School of Medicine, Tel Hashomer 52621, Israel.
Lev Bedrin
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, The Chaim Sheba Medical Center and the Tel-Aviv University Sackler School of Medicine, Tel Hashomer 52621, Israel.
Alexander Waller
Affiliation:
Tel Hashomer Hospice (Israeli Cancer Association), The Chaim Sheba Medical Center and the Tel-Aviv University Sackler School of Medicine, Tel Hashomer 52621, Israel.
Zeev Horowitz
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, The Chaim Sheba Medical Center and the Tel-Aviv University Sackler School of Medicine, Tel Hashomer 52621, Israel.
Yair Skurnik
Affiliation:
General Medicine B, The Chaim Sheba Medical Center and the Tel-Aviv University Sackler School of Medicine, Tel Hashomer 52621, Israel.
Abraham Adunski
Affiliation:
Geriatric Department, The Chaim Sheba Medical Center and the Tel-Aviv University Sackler School of Medicine, Tel Hashomer 52621, Israel.
Jona Kronenberg
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, The Chaim Sheba Medical Center and the Tel-Aviv University Sackler School of Medicine, Tel Hashomer 52621, Israel.
*
Address for correspondence: Yoav P. Talmi, M.D., Department of Otolaryngology – Head and Neck Surgery, The Chain Sheba Medical Center, Tel Hashomer 52621, Israel.
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Abstract

Synchronous or metachronous second primary malignancies of the lung are sometimes encountered in patients with laryngeal cancer while the occurrence of a laryngeal second primary following cancer of the lung is rare.

A two-armed study was conducted. A prospective arm in which the larynges of 56 terminal lung cancer patients were examined, and a retrospective arm incorporating both a chart study of 126 terminal head and neck cancer patients (HNCP) and a computerized search of all hospital records of patients with laryngeal and lung cancers. No laryngeal malignancy was found in the lung cancer patients' group and no antedating pulmonary malignancy was recorded in the terminal HNCP. The computerized search of 1778 lung cancer patients and 213 laryngeal cancer patients also failed to demonstrate cases where the former preceded the latter.

In conclusion. No second primary of the larynx was found in lung cancer patients. These results compare with reports of large databases where cancer of the larynx was found in a negligible percentage of lung cancer survivors and theories explaining this are discussed.

Keywords

Lung neoplasmsLaryngeal neoplasmsNeoplasmssecond primary
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 112 , Issue 3 , March 1998 , pp. 252 - 257
Copyright
Copyright © JLO (1984) Limited 1998

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