Hostname: page-component-586b7cd67f-dsjbd Total loading time: 0 Render date: 2024-11-24T08:44:22.983Z Has data issue: false hasContentIssue false

Scytalidium dimidiatum associated invasive fungal sinusitis in an immunocompetent patient

Published online by Cambridge University Press:  02 October 2014

A Hariri*
Affiliation:
Department of ENT, Charing Cross Hospital, Imperial College Healthcare NHS Trust, UK
N Choudhury
Affiliation:
Department of ENT, Charing Cross Hospital, Imperial College Healthcare NHS Trust, UK
H A Saleh
Affiliation:
Department of ENT, Charing Cross Hospital, Imperial College Healthcare NHS Trust, UK
*
Address for correspondence: Dr Ahmad Hariri, Department of ENT, Charing Cross Hospital, Fulham Palace Road, London W6 9NT, UK Fax: 0203 311 5088 E-mail: [email protected]

Abstract

Background:

Scytalidium dimidiatum is a soil and plant pathogen that frequently affects fruit trees, but can also cause human infection. There are only two reported cases of invasive fungal sinusitis involving this rare micro-organism.

Objective:

This paper reports the first case of invasive fungal sinusitis caused by Scytalidium dimidiatum occurring in a young immunocompetent patient from a non-endemic region, and discusses potential sources of exposure and relevance of local factors.

Method:

Case report.

Results:

The patient was treated successfully with a combination of functional endoscopic sinus surgery, and antifungal and corticosteroid treatment.

Conclusion:

This paper describes the first reported case of invasive fungal sinusitis secondary to Scytalidium dimidiatum in a young immunocompetent patient from a non-endemic region. Importance is placed on following a systematic process of investigation and management, and adhering to well-defined basic surgical principles.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 2014 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Frankel, DH, Rippon, JW. Hendersonula toruloidea infection in man. Index cases in the non-endemic North American host, and a review of the literature. Mycopathologia 1989;105:175–86Google Scholar
2Elinav, H, Izhar, U, Benenson, S, Admon, D, Hidalgo-Grass, C, Polacheck, I et al. Invasive Scytalidium dimidiatum infection in an immunocompetent adult. J Clin Microbiol 2009;47:1259–63Google Scholar
3Turner, JH, Soudry, E, Nayak, JV, Hwang, PH. Survival outcomes in acute invasive fungal sinusitis: a systematic review and quantitative synthesis of published evidence. Laryngoscope 2013;123:1112–18CrossRefGoogle ScholarPubMed
4Chen, CY, Sheng, WH, Cheng, A, Chen, YC, Tsay, W, Tang, JL et al. Invasive fungal sinusitis in patients with hematological malignancy: 15 years experience in a single university hospital in Taiwan. BMC Infect Dis 2011;11:250CrossRefGoogle Scholar
5Almyroudis, N, Sutton, D, Linden, P, Rinaldi, M, Fung, J, Kusne, S. Zygomycosis in solid organ transplant recipients in a tertiary transplant center and review of the literature. Am J Transplant 2006;6:2365–74CrossRefGoogle Scholar
6Sydow, H, Sydow, P, Butler, E. Fungi Indiae orientalis pars V. Annales Mycologici 1916;14:177220Google Scholar
7Khan, Z, Ahmad, S, Joseph, L, Chandy, R. Cutaneous phaeohyphomycosis due to Neoscytalidium dimidiatum: first case report from Kuwait. Journal of Medical Mycology 2009;19:138–42Google Scholar
8Morris-Jones, R, Youngchim, S, Hextall, JM, Gomez, BL, Morris-Jones, SD, Hay, RJ et al. Scytalidium dimidiatum causing recalcitrant subcutaneous lesions produces melanin. J Clin Microbiol 2004;42:3789–94CrossRefGoogle ScholarPubMed
9al-Rajhi, AA, Awad, AH, al-Hedaithy, S, Forster, RK, Caldwell, KC. Scytalidium dimidiatum fungal endophthalmitis. Br J Ophthalmol 1993;77:388–90CrossRefGoogle ScholarPubMed
10Benne, C, Neeleman, C, Bruin, M, De Hoog, G, Fleer, A. Disseminating infection with Scytalidium dimidiatum in a granulocytopenic child. Eur J Clin Microbiol Infect Dis 1993;12:118–21CrossRefGoogle Scholar
11Dunn, JJ, Wolfe, MJ, Trachtenberg, J, Kriesel, JD, Orlandi, RR, Carroll, KC. Invasive fungal sinusitis caused by Scytalidium dimidiatum in a lung transplant recipient. J Clin Microbiol 2003;41:5817–19Google Scholar
12Geramishoar, M, Zomorodian, K, Zaini, F, Saadat, F, Tarazooie, B, Norouzi, M et al. First case of cerebral phaeohyphomycosis caused by Nattrassia mangiferae in Iran. Jpn J Infect Dis 2004;57:285–6Google Scholar
13Gumbo, T, Mkanganwi, N, Robertson, VJ, Masvaire, P. Case report. Nattrassia mangiferae endophthalmitis. Mycoses 2002;45:118–19CrossRefGoogle ScholarPubMed
14Mani, RS, Chickabasaviah, YT, Nagarathna, S, Chandramuki, A, Shivprakash, MR, Vijayan, J et al. Cerebral phaeohyphomycosis caused by Scytalidium dimidiatum: a case report from India. Med Mycol 2008;46:705–11CrossRefGoogle ScholarPubMed
15Sadeghi Tari, A, Mardani, M, Rahnavardi, M, Asadi Amoli, F, Abedinifar, Z. Post-traumatic fatal Nattrassia mangiferae orbital infection. Int Ophthalmol 2005;26:247–50CrossRefGoogle ScholarPubMed
16Tan, DHS, Sigler, L, Gibas, CFC, Fong, IW. Disseminated fungal infection in a renal transplant recipient involving Macrophomina phaseolina and Scytalidium dimidiatum: case report and review of taxonomic changes among medically important members of the Botryosphaeriaceae. Med Mycol 2008;46:285–92Google Scholar
17Willinger, B, Kopetzky, G, Harm, F, Apfalter, P, Makristathis, A, Berer, A et al. Disseminated infection with Nattrassia mangiferae in an immunosuppressed patient. J Clin Microbiol 2004;42:478–80CrossRefGoogle Scholar
18Ikram, A, Hussain, W, Satti, ML, Wiqar, MA. Invasive infection in a young immunocompetent soldier caused by Scytalidium dimidiatum. J Coll Physicians Surg Pak 2009;19:64–6Google Scholar