Hostname: page-component-586b7cd67f-dsjbd Total loading time: 0 Render date: 2024-12-01T00:08:48.974Z Has data issue: false hasContentIssue false
  • English
  • Français

Salivary gland involvement in Wegener's granulomatosis

Published online by Cambridge University Press:  29 June 2007

G. E. Murty ,
B. T. Mains  and
M. K. Bennett
G. E. Murty*
Affiliation:
Department of ENTFreeman Hospital, Newcastle upon Tyne
B. T. Mains
Affiliation:
Department of ENTRoyal Victoria Hospital, Belfast
M. K. Bennett
Affiliation:
Department of Pathology, Freeman Hospital, Newcastle upon Tyne.
*
George E. Murty, ENT Department, Freeman Hospital, Freeman Rd. High Heaton, Newcastle upon Tyne NE7 7DN.
Get access Rights & Permissions [Opens in a new window]

Abstract

When salivary gland enlargement occurs in association with other ENT symptoms, Wegener's granulomatosis should be considered in the differential diagnosis. An early anti-neutrophil cytoplasmic antibody (ANCA) test may aid diagnosis. Effective medical treatment exists and, once the diagnosis has been made, therapeutic excision of the affected gland may be unnecessary. The fourth and fifth cases in the literature of salivary gland involvement in Wegener's granulomatosis are reported.

Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 104 , Issue 3 , March 1990 , pp. 259 - 261
Copyright
Copyright © JLO (1984) Limited 1990

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Berman, D. A., Rydell, R. E., Eichenholz, A. (1963) Wegener's granulomatosis: A Clinico-pathologic study of four cases. Annals of Internal Medicine, 59: 521–530.CrossRefGoogle ScholarPubMed
Borleff, J. C. C., Derksen, R. H. W. M., Hene, R. J. (1987) Treatment of Wegener's granulomatosis with cyclosporin. Annals of Rheumatic Diseases, 42(2): 175.CrossRefGoogle Scholar
Brown, H. A., Woolmer, L. B. (1960) Findings referrable to the upper part of the respiratory tract in Wegener's granulomatosis. Annals of Otology, Rhinology and Laryngology, 69: 810–829.CrossRefGoogle Scholar
Carrington, C. B., Liebow, A. A. (1966) Limited forms of angiitis and granulomatosis of Wegener's type. American Journal of Medicine, 41: 497–527.CrossRefGoogle ScholarPubMed
Cassan, S. M., Coles, D. J., Harrison, E. G. Jr (1970) The concept of limited forms of Wegener's granulomatosis. American Journal of Medicine, 49: 366–379.CrossRefGoogle ScholarPubMed
DeRemee, R. A., McDonald, T. J., Weiland, L. H. (1985) Wegener's granulomatosis: observation on treatment with antimicrobial agents. Mayo Clinic Proceedings, 60: 27–32.CrossRefGoogle ScholarPubMed
Fahey, J., Leonard, E., Churg, J., Godman, G. (1954) Wegener's granulomatosis. American Journal of Medicine, 17: 169–179.CrossRefGoogle ScholarPubMed
Fauci., A. S., Haynes, B. F., Katz, P., Wolff, S. M. (1983) Wegener's granulomatosis: Prospective clinical and therapeutic experience with 85 patients for 21 years. Annals of Internal Medicine, 98: 76–85.CrossRefGoogle ScholarPubMed
Fukuda, K., Yuasa, K., Uchizoner, A., Matsuyama, H., Shimada, K., Ohyama, M. (1989) Three cases of Wegener's granulomatosis with an antimicrobial agent. Archives of Otolaryngology–Head and Neck Surgery, 115: 515–518.CrossRefGoogle ScholarPubMed
Godman, G. C., Churg, J. (1954) Wegener's granulomatosis: Pathology and review of the literature. Archives of Pathology, 58: 533–553.Google ScholarPubMed
Gremmel, F., Drurnl, W., Schmidt, P., Grainger, W. (1988) Cyclosporin in Wegener's granulomatosis. Annals of Internal Medicine, 108(3): 491.CrossRefGoogle Scholar
Gross, W. L., Luderman, G., Kiefer, G., Lehmam, H. (1986) Anti-cytoplasmic antibodies in Wegener's granulomatosis. Lancet, 1: 806.CrossRefGoogle Scholar
Israel, H. L. (1988) Sulfamethoxazole–Trimethoprim therapy for Wegener's granulomatosis. Archives of Internal Medicine 148: 2293–2295.CrossRefGoogle ScholarPubMed
Klinger, H. (1931) Grenzfomen der Periarteritis Nodosa. Frankfurter Zeitschrift Pathologie, 42: 455–480.Google Scholar
Lockwood, C. M., Jones, S., Moss, D. W., Bakes, D., Whitaker, K. B., Savage, C. O. S. (1987) Association of alkaline phosphatase with an autoantigen recognized by circulating anti-neutrophil antibodies in systemic vasculitis. Lancet, 1: 716–720.CrossRefGoogle ScholarPubMed
Small, P., Black, M., Davidman, M., Champlain, M. L. B. de, Kapusta, M. A.Kreisman, H. (1980) Wegener's granulomatosis and relapsing polychrondritis: A case report. Journal of Rheumatology, 7: 915–918.Google Scholar
Spiera, H., Lawson, W., Weinrauch, H. (1988) Wegener's granulomatosis treated with Sulfamethoxazole-Trimethoprim. Archives of Internal Medicine, 148: 2065–2067.CrossRefGoogle ScholarPubMed
Van der Woude, F. J., Rasmussen, N., Lobatto, S., Wiik, A., Permin, H., Van Es., L. A., Van der Giessen, M., Van der Hern, G. K., The, T. H. (1985) Autoantibodies against neutrophils and monocytes. Tool for diagnosis and marker of disease activity in Wegener's granulomatosis. Lancet, 1: 425–429.CrossRefGoogle ScholarPubMed
Walton, E. W. (1958) Giant-cell granuloma of the respiratory tract (Wegener's granulomatosis) British Medical Journal, 2: 265–270.CrossRefGoogle ScholarPubMed
Walton, E. W., Leggat, P. O. (1956) Wegener's Granulomatosis. Journal of Clinical Pathology, 9: 31–37.CrossRefGoogle ScholarPubMed
Wegener, F. (1936) Ūber generalisierte, septische Gefāsserkramkungen Verhandlungen, der Deutschen Gesellschaft fur Pathologie, 29: 202–210.Google Scholar
Wegener, F. (1939) Über eine Eigenartige Rhinogene Granulomatose mit besonderer Beteiligung der Arteriensystems und der Nieren. Beitrage zur Pathologischen Anatomie und zur Allgemeinen Pathologie, 102: 36–38.Google Scholar
Wegener, F. (1966) In: Lehrbuch der speziellen Pathologischen Anatomie Straemmler, M. M. (Ed) Vol 1/1 P.226De Gruyter, Berlin.Google Scholar
West, B. C., Todd, J. R., King, J. W. (1987) Wegener's granulomatosis and Trimethoprim-Sulfamethoxazole. Annals of Internal Medicine, 106: 840–842.CrossRefGoogle ScholarPubMed