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Rosai-Dorfman disease presenting as a parotid mass

Published online by Cambridge University Press:  29 June 2007

L. Norman ,
A. C. Bateman ,
G. W. R. Watters ,
V. Singh  and
A. V. Spedding
L. Norman
Affiliation:
Department of Otolaryngology, Queen Alexandra Hospital, Cosham, Portsmouth, UK
A. C. Bateman*
Affiliation:
Department of Histopathology, Queen Alexandra Hospital, Cosham, Portsmouth, UK
G. W. R. Watters
Affiliation:
Department of Otolaryngology, Queen Alexandra Hospital, Cosham, Portsmouth, UK
V. Singh
Affiliation:
Department of Otolaryngology, Queen Alexandra Hospital, Cosham, Portsmouth, UK
A. V. Spedding
Affiliation:
Department of Histopathology, Queen Alexandra Hospital, Cosham, Portsmouth, UK
*
Address for correspondence: Dr A. C. Bateman, Department of Histopathology, Level E, South Block, Southampton General Hospital, Tremona Road, Southampton SO16 6YD. Fax: 01703 796869
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Abstract

Sinus histiocytosis with massive lymphadenopathy (SHML) is a rare, benign disease of unknown aetiology. This disease typically presents with massive, painless cervical lymphadenopathy but may occur in a wide variety of extranodal sites. Our report describes a 71-year-old man who presented with a discrete, unilateral parotid mass which was clinically suggestive of a primary salivary gland tumour. Initial cytological examination of a fine needle aspirate specimen taken from the mass demonstrated a discohesive cell population with nuclear atypia, raising the possibility of malignancy. However, excision of the mass and histological examination enabled a definitive diagnosis to be made.

Keywords

Histiocytosis, sinusLymph nodeNeck
Type
Pathology in Focus
Information
The Journal of Laryngology & Otology , Volume 111 , Issue 11 , November 1997 , pp. 1091 - 1093
Copyright
Copyright © JLO (1984) Limited 1997

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References

Foucar, E., Rosai, J., Dorfman, R. F. (1990) Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman Disease): review of the entity. Seminars in Diagnostic Pathology 7: 19–73.Google ScholarPubMed
Goodnight, J. W., Wang, M. B., Sercarz, J. A., Fu, Y. S. (1996) Extranodal Rosai-Dorfman Disease of the head and neck. Laryngoscope 106: 253–256.Google Scholar
Hammond, L. A., Keh, C., Rowlands, D. C. (1996) Rosai-Dorfman disease in the breast. Histopathology 29: 582–584.CrossRefGoogle ScholarPubMed
Horneff, G., Jurgens, H., Hort, W., Karitzy, D., Gobel, U. (1996) Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): response to methotrexate and mercaptopurine. Medical and Pediatric Oncology 27: 187–192.Google Scholar
Komp, D. M. (1990) The treatment of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease). Seminars in Diagnostic Pathology 7: 83–86.Google ScholarPubMed
Levine, P. H., Jahan, N., Murari, P., Manak, M., Jaffe, E. S. (1992) Detection of human herpesvirus 6 in tissues involved by sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman Disease). Journal of Infectious Diseases 166: 291–295.CrossRefGoogle ScholarPubMed
McAlister, W. H., Herman, T., Dehner, L. P. (1990) Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorf-man Disease). Paediatric Radiology 20: 425–432.CrossRefGoogle ScholarPubMed
Naidu, R. K., Urken, M. L., Som, P. M., Danon, A., Biller, H. F. (1990) Extranodal head and neck sinus histiocytosis with massive lymphadenopathy. Otolaryngology – Head and Neck Surgery 102: 764–767.Google Scholar
Rosai, J., Dorfman, R. F. (1969) Sinus Histiocytosis with massive lymphadenopathy: a newly recognised benign clinicopathological entity. Archives of Pathology 87: 63–70.Google ScholarPubMed
Rosai, J., Dorfman, R. F. (1972) Sinus histiocytosis with massive lymphadenopathy: A pseudolymphomatous benign disorder. Analysis of 34 cases. Cancer 30: 1174–1188.Google Scholar
Trautman, B. C., Stanley, M. W., Goding, G. S., Rosai, J. (1991) Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman Disease): diagnosis by fine needle aspiration. Diagnostic Cytopathology 7: 513–516.Google Scholar