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Role of irradiation in the suppression of parotid secretions

Published online by Cambridge University Press:  29 June 2007

A. C. R. Robinson*
Affiliation:
Department of Radiotherapy, University of Leeds, Cookridge Hospital, Leeds LS16 6QB.
G. G. Khoury
Affiliation:
Department of Radiotherapy, University of Leeds, Cookridge Hospital, Leeds LS16 6QB.
P. M. Robinson
Affiliation:
Department of ENT, University of Leeds, Leeds General Infirmary, Great George Street, Leeds LS1 3EX.
*
Dr A. C. R. Robinson, The Christie Hospital and Holt Radium Institute, Wilmslow Road, Withington, Manchester M20 9BX.

Abstract

Suppression of salivary flow is of value in the management of salivary fistulae and sialectasia. It may also be beneficial in mentally defective patients and those with neurological palsies lacking control of their salivation. Nine patients were treated by irradiation to the parotid gland to control salivary flow; eight had complete resolution of symptoms and one had partial relief. Irradiation was effective as primary treatment and after failed surgery and/or drug treatment. Low doses were effective and there were no significant acute or long-term side effects. Its use avoids long-term medication and their potential side effects and may reduce the need for surgery.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 1989

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References

Barbera, G. (1936) Roentgen treatment of salivary fistula. Policlinico (Sezione Pratica), 43: 17731776.Google Scholar
Bailey, C. M. and Wadsworth, P. V. (1985) Treatment of the drooling child by submandibular duct transposition. Journal of Laryngology and Otology, 99: 11111117.CrossRefGoogle ScholarPubMed
Cheng, V. S. T., Downs, J., Herbert, D. and Aramany, M. (1981) The function of the parotid gland following radiation therapy for head and neck cancer. International Journal of Radiation Oncology Biology Physics, 7: 253258.CrossRefGoogle ScholarPubMed
Dawes, C. and Ong, B. Y. (1973) Circadian rhythms in flow rate and proportional contribution of parotid to whole saliva volume in man. Archives of Oral Biology, 18: 11451153.CrossRefGoogle ScholarPubMed
Frank, R. M., Herdly, J. and Philippe, E. (1965) Acquired dental defects and salivary gland lesions after irradiation for carcinoma. Journal of American Dental Association, 70: 868883.CrossRefGoogle ScholarPubMed
Mandour, M. A., El-Sheik, M. M. and El-Garem, F. (1976) Tympanic neurectomy for parotid fistula. Archives of Otolaryngology, 102: 327329.CrossRefGoogle ScholarPubMed
Morgan, W. R. (1973) Parotid duct ligation and tympanic neurectomy. Archives of Otolaryngology, 98: 179182.CrossRefGoogle ScholarPubMed
Schindel, I., Markowicz, H. and Levie, B. (1968) Combined surgical-radiological treatment of parotid gland fistulae. Journal of Laryngology and Otology, 82: 867870.CrossRefGoogle ScholarPubMed
Schneyer, L. H. and Levin, L. K. (1954) Rate of secretion of individual salivary gland pairs in men under two conditions of stimulation. Journal of Dental Research, 33: 716717.Google Scholar
Shannon, I. L., Trodahl, J. N. and Starcke, E. N. (1978) Radiosensitivity of the human parotid gland. Proceedings of the Society for Experimental Biology and Medicine, 157: 5053.CrossRefGoogle ScholarPubMed
Stephens, L. C., Ang, K. K., Schultheiss, T. E., King, G. K., Brock, W. A. and Peters, L. J. (1986) Target cell and mode of radiation injury in rhesus salivary glands. Radiotherapy and Oncology, 7: 165174.CrossRefGoogle ScholarPubMed