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Rheumatoid nodules of the larynx

Published online by Cambridge University Press:  29 June 2007

Waldemar Trolle Sørensen ,
Kim Møller-Andersen  and
Nille Behrendt
Waldemar Trolle Sørensen*
Affiliation:
Department of Otolaryngology, Glostrup Hospital, Copenhagen, Denmark.
Kim Møller-Andersen
Affiliation:
Department of Otolaryngology, Glostrup Hospital, Copenhagen, Denmark.
Nille Behrendt
Affiliation:
Department of Otolaryngology, Glostrup Hospital, Copenhagen, Denmark.
*
Address for correspondence: Waldemar Trolle Sørensen M.D. Frugthegnet 46, 2830 Virum, Denmark.
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Abstract

A 67-year-old woman with rheumatoid arthritis was hospitalized because of dysphagia and severe nodulosis. Over a two-year period the patient had been treated with methotrexate. A computed tomography (CT) scan of the neck showed a 2 × 2 cm large tumour behind the top left lateral thyroid cartilage. A biopsy taken during direct laryngoscopy showed it was a rheumatic nodule. Treatment with colchicine reduced the patient's dysphagia. As methotrexate is used increasingly in the treatment of rheumatoid arthritis and as this particular drug causes rheumatic nodules in five to 10 per cent of the patients, it must be foreseen that the incidence of nodules in the upper airways will increase.

Keywords

Arthritis, rheumatoidLarynxRheumatic noduleDeglutition disordersMethotrexate
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 112 , Issue 6 , June 1998 , pp. 573 - 574
Copyright
Copyright © JLO (1984) Limited 1998

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References

Abadir, F., Forster, P. (1974) Rheumatoid vocal cord nodules. Journal of Laryngology 88: 473–478.CrossRefGoogle ScholarPubMed
Bridger, M., Jahn, A. (1980) Laryngeal rheumatoid arthritis. Laryngoscope 90: 296–303.CrossRefGoogle ScholarPubMed
Bruce, A., Dale, H. (1975) Rheumatoid nodules of the larynx. Archives of Otolaryngology, Head and Neck Surgery 101: 361–363.Google Scholar
Edelist, G. (1964) Principles of anesthetic management in rheumatoid arthritic patients. Anesthesia and Analgesia 43: 227–231.CrossRefGoogle ScholarPubMed
Kerstens, P., Boerbooms, A. (1992) Accelerated nodulosis during low dose methotrexate therapy for rheumatoid arthritis. Journal of Rheumatology 19: 867–871.Google ScholarPubMed
Lofgren, R., Montgomery, W. (1962) Incidence of laryngeal involvement in rheumatoid arthritis. New England Journal of Medicine 267: 193–195.CrossRefGoogle ScholarPubMed
Merrill, B. N., Shen, C. (1996) Reversal of new but not old rheumatoid nodules by coichicine: evidence from an in vitro model and case reports of 14 patients. Arthritis and Rheumatism 39: 240.Google Scholar
Phelps, J. (1966) Laryngeal obstruction due to cricoarytenoid arthritis. Anesthesiology 27: 518–22.CrossRefGoogle ScholarPubMed
Polisar, I. (1959) The crico-arytenoid joint. Laryngoscope 69: 1129–1164.CrossRefGoogle ScholarPubMed
Webb, J., Payne, W. (1972) Rheumatoid nodules of the vocal folds. Annals of the Rheumatic Diseases 31: 122–125.CrossRefGoogle ScholarPubMed
Woo, P., Mendelsohn, J.. Humphrey, D. (1995) Rheumatoid nodules of the larynx. Otolaryngology – Head and Neck Surgery 113: 147–150.CrossRefGoogle ScholarPubMed