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Recovery from rhinocerebral mucormycosis in a ketoacidotic diabetic patient: a case report

Published online by Cambridge University Press:  29 June 2007

J. Kemper*
Affiliation:
Department of Otolaryngology/Head and Neck Surgery, Amsterdam, The Netherlands.
E. J. Kuijper
Affiliation:
Department of Medical Microbiology, Amsterdam, The Netherlands.
P. G. B. Mirck
Affiliation:
Department of Otolaryngology/Head and Neck Surgery, Amsterdam, The Netherlands.
A. J. M. Balm
Affiliation:
Academic Medical Centre, University of Amsterdam and the Netherlands Cancer Institute, Amsterdam, The Netherlands.
*
J. Kemper, Department of Otolaryngology/Head and Neck Surgery, Academic Medical Centre, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands

Abstract

An 18-year-old woman with insulin-dependent diabetes mellitus developed an infection of the paranasal sinuses with Rhizopus oryzae resulting in facial swelling, hemiplegia and blindness of the right eye. The therapy of this rhinocerebral mucormycosis consisted of extensive surgical debridement, administration of high-dose amphotericin B, hyperbaric oxygen and control of the underlying predisposing diabetes mellitus. The patient eventually recovered with however, the loss of one eye.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1993

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References

Armstrong, D. (1989) Problems in management of opportunistic fungal diseases. Reviews of Infectious Diseases 11: 15911599.Google Scholar
Couch, L., Theilen, F, Mader, J. T. (1988) Rhinocerebral muconnycosis with cerebral extension successfully treated with adjunctive hyerbaric oxygen therapy. Archives of Otolaryngology and Head, Neck Surgery 114: 791794.Google Scholar
Ferguson, B. J., Mitchell, T. G., Moon, R., Camporesi, E. M., Farmer, J. (1988) Adjunctive hyperbaric oxygen for treatment of rhinocerebral mucormycosis. Reviews of Infectious Diseases 10: 551559.CrossRefGoogle ScholarPubMed
Finn, D. G. (1988) Mucormycosis of the paranasal sinuses. Ear, Nose and Throat Journal 67: 813822.Google ScholarPubMed
Hunt, T. K., Zedenfeldi, B., Goldstick, T. K. (1969) Oxygen and healing. American Journal of Surgery 118: 521525.CrossRefGoogle ScholarPubMed
Lehrer, R. I. (1980) Mucormycosis. Annals of Internal Medicine 93: 93108.Google Scholar
Nathan, M. D., Keller, A. P., Lemer, C. J., Davis, J. C. (1982) Entomophthorales infection of the maxillofacial region. Laryngoscope 92: 767769.Google Scholar
Orsel, S., Bessede, J. P., Sauvage, J. P. (1990) Mucormycose naso orbito cerebrale. Une maladie de moms en moms exceptionnelle. Revue de Laryngologie 111: 221225.Google Scholar
Paltauf, A. (1885) Mycosis mucorina. Virchows Archives (Pathology and Anatomy) 102: 543.Google Scholar
Price, J. C., Stevens, D. L. (1980) Hyperbaric oxygen in the treatment of rhinocerebral mucormycosis. Laryngoscope 90: 737747.Google Scholar
Robb, S. M. (1966) Reactions of fungi to exposure to 10 atmospheres pressure of oxygen. Journal of General Microbiology 45: 1729.Google Scholar
Schipper, M. A. A. (1978) Studies in mycology, no. 17. In Centraal bureau voor schimmelcultures. (Baarn, , ed.)Google Scholar
Scholer, H. J. (1983) Mucorales. In Fungi pathogenic for humans and animals. (Howard, D. H., ed), New York, p. 959.Google Scholar
Tange, R. A., Nijdam, D. C., Schot, L., Schipper, M. E., Bras, J. (1986) Localized aspergillosis involving the nose and paranasal sinusis. Acta Oto-Rhino-Laryngologica Belgica 40: 455462.Google Scholar
Tyagi, I., Majumder, N. K., Gopalakrishan, S. (1990) Mucormycosis of paranasal sinuses. Pakistan Journal of Otolaryngology 1: 3741.Google Scholar
Venezio, F. R., Tucker, P. C. (1988) Zygomycosis. In Handbook of Clinical Neurology 8, (Harris, A. A., ed.) Elsevier Science Publishers, Amsterdam. p. 467477.Google Scholar
Wachsmuth, E. D. (1988) Visualization of fungi in histological sections. Virchows Archives (Cell Pathology) 56: 14.CrossRefGoogle ScholarPubMed