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Radiotherapeutic effect on oropharyngeal flora in patients with head and neck cancer

Published online by Cambridge University Press:  29 June 2007

K. A. Abu Shara ,
M. A. Ghareeb ,
S. Zaher ,
A. Mobacher ,
M. Ch. Khalifa  and
S. Z. Saleh
K. A. Abu Shara*
Affiliation:
Cairo, Egypt
M. A. Ghareeb
Affiliation:
Cairo, Egypt
S. Zaher
Affiliation:
Cairo, Egypt
A. Mobacher
Affiliation:
Cairo, Egypt
M. Ch. Khalifa
Affiliation:
Cairo, Egypt
S. Z. Saleh
Affiliation:
Cairo, Egypt
*
Khairy Alhag Abu Shara, P.O. 3833, Hawally 32069, Kuwait.
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Abstract

The affect of radiotherapy on oropharyngeal bacterial flora was studied in the hope that this might help in controlling post-operative infections in previously irradiated patients. Eighty patients were included from whom swabs were taken before and at the end of irradiation, Swabs were also taken two weeks after treatment in the last 40 patients. Thirty healthy controls were included.

It was found that coagulase positive Staphylococcus aureus, β-haemolytic streptococci, Candida albicans, B. proteus, and Pseudomonas aeruginosa, were significantly increased at the end of irradiation, while Klebsiella was increased significantly in the period after irradiation. Culture and sensitivity was performed for the organisms isolated in the last 40 patients.

From this study it is evident that irradiation has a significant effect on oropharyngeal flora.

Keywords

Head and neck neoplasmsRadiotherapyMicrobiology
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 107 , Issue 3 , March 1993 , pp. 222 - 227
Copyright
Copyright © JLO (1984) Limited 1993

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