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Primary tumours of the trachea: analysis of clinical features and treatment results

Published online by Cambridge University Press:  29 June 2007

David J. Howard  and
Vijay V. Haribhakti
David J. Howard*
Affiliation:
professorial Unit, The Royal National Throat, Nose and Ear Hospital, London.
Vijay V. Haribhakti
Affiliation:
professorial Unit, The Royal National Throat, Nose and Ear Hospital, London.
*
Mr David J. Howard, The Royal National Throat, Nose and Ear Hospital, 330/332 Gray's Inn Road, WC1X 8DA. Fax: 071 833 9480
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Abstract

Primary tracheal tumours are extremely rare and present with widely variant clinical and histological features. Treatment methods vary considerably, and few studies have sought to provide adequate guidelines. A retrospective analysis was carried out of all patients treated in our unit between 1965 and 1990. Our experience deals almost exclusively with high tracheal tumours involving the adjacent subglottic region. Squamous carcinoma (SCC) and adenoid cystic carcinoma (ACC) were the commonest subtypes, and presented with dyspnoea and hoarseness as the most frequent symptoms. ACCs occurred commonly in young individuals, presented insidiously, and ran a long, and often, unpredictable course. Endoscopic evaluation revealed the majority of the lesions to be bulky and obstructive in nature. Primary surgery with adjuvant radical radiotherapy, when indicated, appeared to provide optimal results. Debulking surgery followed by radiotherapy provided effective and lasting control in two cases of ACC. Other malignant subtypes behaved aggressively and progressed uncontrolled.

Keywords

Tracheal neoplasms
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 108 , Issue 3 , March 1994 , pp. 230 - 232
Copyright
Copyright © JLO (1984) Limited 1994

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