Hostname: page-component-cd9895bd7-gvvz8 Total loading time: 0 Render date: 2024-12-26T20:29:03.323Z Has data issue: false hasContentIssue false
  • English
  • Français

Primary otological manifestations of granulomatosis with polyangiitis: a case series

Published online by Cambridge University Press:  19 February 2015

N Amiraraghi ,
S Robertson  and
A Iyer
N Amiraraghi*
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, NHS Lanarkshire, Airdrie, Lanarkshire, UK
S Robertson
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, NHS Greater Glasgow, Scotland, UK
A Iyer
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, NHS Lanarkshire, Airdrie, Lanarkshire, UK
*
Address for correspondence: Ms N Amiraraghi, Ward 20, Otolaryngology Department, Royal Alexandra Hospital, Corsebar Road, Paisley PA2 9PN, Scotland, UK E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Objectives:

A primary otological presentation of granulomatosis with polyangiitis is rare. We present four cases of granulomatosis with polyangiitis with different otological manifestations.

Case report:

A literature review of granulomatosis with polyangiitis cases presenting to otolaryngologists was undertaken. A case series review of four patients presenting within a 12-month period was also performed. One patient had serous otitis media which worsened after myringotomy. Two patients presented with acute ear infection and facial palsy and one with acute mastoiditis. All were positive for antineutrophilic cytoplasmic antibody, and three had positive findings upon histological analysis.

Conclusion:

When acute supposed ear infections fail to respond to treatment (antibiotics or surgery), rarer causes of the symptoms should be considered. By reporting this case series, we aim to improve the early diagnosis of granulomatosis with polyangiitis to enable timely treatment and prevent systemic involvement.

Keywords

Wegener's GranulomatosisOtologic DiseasesOtitis Media
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 129 , Issue 2 , February 2015 , pp. 179 - 182
Copyright
Copyright © JLO (1984) Limited 2015 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

Presented at the British Academic Conference in Otolaryngology, 4–6 July 2012, Glasgow, Scotland, UK.

References

1Falk, RJ, Gross, WL, Guillevin, L, Hoffman, G, Jayne, DR, Jennette, JC et al. Granulomatosis with polyangitis (Wegener's): an alternative name for Wegener's granulomatosis. Ann Rheum Dis 2011;70:704Google Scholar
2McDonald, TJ, DeRemee, RA. Wegener's granulomatosis. Laryngoscope 1983;93:220–31Google Scholar
3Ito, Y, Shinogi, J, Yuta, A, Okada, E, Taki, M, Matsukage, H. Clinical records: a case report of Wegener's granulomatosis limited to the ear. Auris Nasus Larynx 1991;18:281–9Google Scholar
4McCaffrey, TV, McDonald, TJ, Facer, GW, DeRemee, RA. Otologic manifestations of Wegener's granulomatosis. Otolaryngol Head and Neck Surg 1980;88:586–93Google Scholar
5Gubbels, SP, Barkhuizen, A, Hwang, PH. Head and neck manifestations of Wegener's granulomatosis. Otolaryngol Clin North Am 2003;36:685–705Google Scholar
6Dagnum, P, Robertson, JB Jr. Otologic Wegener's granulomatosis with facial nerve palsy. Ann Otol Rhinol Laryngol 1998;107:555–9Google Scholar
7Nikoloua, AC, Vlachtsis, KC, Daniilidis, MA, Petridis, DG, Daniilidis, IC. Wegener's granulomatosis presenting with bilateral facial nerve palsy. Eur Arch Otorhinolaryngol 2001;258:198–202Google Scholar
8Takagi, D, Nakamaru, Y, Maguchi, S, Furuta, Y, Fukada, S. Otologic manifestations of Wegener's granulomatosis. Laryngoscope 2002;112:1684–90Google Scholar
9Tsuzki, K, Fukazawa, K, Takebayashi, H, Hashimoto, K, Sakagami, M. Difficulty of diagnosing Wegener's granulomatosis in the head and neck region. Auris Nasus Larynx 2009;36:64–70Google Scholar
10Preuss, S, Stenner, M, Beutner, D, Laudes, M, Klussmann, JP. Fatal course of Wegener's granulomatosis with bilateral otomastoiditis and bilateral facial nerve palsy. Otolaryngol Head Neck Surg 2008;138:799–800Google Scholar
11Ferri, E, Armato, E, Capuzzo, P, Cavaleri, S, Ianniello, F. Early diagnosis of Wegener's granulomatosis presenting with bilateral facial paralysis and bilateral serous otitis media. Auris Nasus Larynx 2007;34:379–82Google Scholar