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Primary non-Hodgkin's lymphoma of the larynx in an AIDS patient

Published online by Cambridge University Press:  29 June 2007

Ricard Simo ,
Christopher Hartley ,
Tass Malik ,
Godfrey E. Wilson ,
Peter H. Taylor  and
Bibhat K. Mandal
Ricard Simo*
Affiliation:
Departments of Otorhinolaryngology and Head and Neck Surgery, North Manchester General Hospital, Manchester, UK.
Christopher Hartley
Affiliation:
Departments of Otorhinolaryngology and Head and Neck Surgery, North Manchester General Hospital, Manchester, UK.
Tass Malik
Affiliation:
Departments of Otorhinolaryngology and Head and Neck Surgery, North Manchester General Hospital, Manchester, UK.
Godfrey E. Wilson
Affiliation:
Departments of Histopathology, North Manchester General Hospital, Manchester, UK.
Peter H. Taylor
Affiliation:
Departments of Otorhinolaryngology and Head and Neck Surgery, North Manchester General Hospital, Manchester, UK.
Bibhat K. Mandal
Affiliation:
Departments of Infectious Diseases, North Manchester General Hospital, Manchester, UK.
*
Address for correspondence: Mr Ricard Simo, F.R.C.S., 12 Rutland Road, Worsley, Manchester M28 7DT.
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Abstract

A case of primary non-Hodgkin's lymphoma of the larynx in an AIDS patient is presented with a review of the literature. Non-Hodgkin's lymphomas in AIDS patients are common but the primary laryngeal presentation is very rare. The symptoms usually include dysphonia and progressive airway obstruction requiring tracheostomy. As with laryngeal non-Hodgkin's laryngeal lymphomas in non-HIV positive patients the majority are of B cell lineage and respond well to radiotherapy. Our patient had a high grade lymphoma of B cell lineage which showed a good response to radiotherapy. The role of chemotherapy and surgery is not yet established. We suggest that the diagnosis of AIDS should not influence the management of these patients unless the individual is in the terminal disease stage.

Keywords

Laryngeal neoplasmsLymphoma, non-Hodgkin'sAcquired Immunodeficiency Syndrome (AIDS)
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 112 , Issue 1 , January 1998 , pp. 77 - 80
Copyright
Copyright © JLO (1984) Limited 1998

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