Hostname: page-component-586b7cd67f-gb8f7 Total loading time: 0 Render date: 2024-11-24T14:37:00.800Z Has data issue: false hasContentIssue false

Primary extramedullary plasmacytoma of the parotid gland: a case report and review of the literature

Published online by Cambridge University Press:  29 June 2007

J. Gonzalez-Garcia*
Affiliation:
Department of Otolaryngology, West Middlesex University Hospital, Isleworth, Middlesex, UK.
K. Ghufoor
Affiliation:
Department of Otolaryngology, West Middlesex University Hospital, Isleworth, Middlesex, UK.
G. Sandhu
Affiliation:
Department of Otolaryngology, West Middlesex University Hospital, Isleworth, Middlesex, UK.
P. A. Thorpe
Affiliation:
Department of Histopathology, West Middlesex University Hospital, Isleworth, Middlesex, UK.
J. Hadley
Affiliation:
Department of Otolaryngology, West Middlesex University Hospital, Isleworth, Middlesex, UK.
*
Address for correspondence: Dr J. Gonzalez-Garcia, Department of Otolaryngology, West Middlesex University Hospital, Twickenham Road, Isleworth, Middlesex TW7 6AF.

Abstract

Solitary extramedullary plasmacytomas are uncommon malignant neoplasms with a great predilection for the upper respiratory tract. Extramedullary plasmacytoma involving the parotid gland is an extremely rare condition. This report describes the case of a primary extramedullary plasmacytoma arising in the right parotid gland of a 63-year-old man. A review of the literature reveals that this disease has generally a good prognosis, provided that multiple myeloma has been excluded. The treatment of choice should be surgical excision followed by radiotherapy, although from this study there is insufficient evidence to suggest that this is more effective than surgery alone. All patients must have regular long-term follow-up to monitor for recurrence or dissemination, in which event chemotherapy may be considered in addition to the other treatment modalities.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1998

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Chiu, W. L., Shih, L. Y., Dunn, P., Chen, L. H. (1994) Extramedullary plasmacytoma of the head and neck. Chang Keng I Hsueh 17: 378383.Google ScholarPubMed
Ebbers, J. (1986) Ein Plasmazytom der Ohrspeicheldruse. Laryngologie Rhinologie und Otologie (Stuttgart) 65: 127129.CrossRefGoogle Scholar
Edney, J. A., Thompson, J. S., Conley, M. C., Moore, G. (1985) Plasmacytoma of the parotid gland. Journal of Surgical Oncology 28: 165167.CrossRefGoogle ScholarPubMed
Ferlito, A., Palidoro, F., Rechner, G. (1980) Extramedullary plasmacytoma of the parotid gland. Laryngoscope 90: 486493.CrossRefGoogle ScholarPubMed
Gleeson, M. (1997) Malignant salivary gland tumours. In Scott Brown's Otolaryngology Laryngology and Head and Neck Surgery. 6th Edition, vol. 5, (Kerr, A. G., Hibbert, J., eds.). Butterworth-Heinemann, Oxford, p 21.Google Scholar
Kanoh, T., Hattori, N., Uchino, H., Fujita, A., Ohmura, M., Makimoto, K. (1985) Extramedullary plasmacytoma of the parotid gland: Report of a case and review of the literature. Tohoku Journal of Experimental Medicine 146: 469478.CrossRefGoogle ScholarPubMed
Kerr, P. D., Dort, J. C. (1991) Primary extramedullary plasmacytoma of the salivary glands. Journal of Laryngology and Otology 105: 687692.CrossRefGoogle ScholarPubMed
Pahor, A. L. (1977) Extramedullary plasmacytoma of the head and neck, parotid, and submandibular salivary glands. Journal of Laryngology and Otology 91: 241258.CrossRefGoogle ScholarPubMed
Rothfield, R. E., Johnson, J. T., Stavrides, A. (1990) Extramedullary plasmacytoma of the parotid. Head and Neck 12: 352354.CrossRefGoogle ScholarPubMed
Scholl, P., Jafek, B. W. (1986) Extramedullary plasmacytoma of the parotid gland. Ear, Nose and Throat Journal 65: 2934.Google ScholarPubMed
Simi, U., Marchetti, G., Bruno, R., DiNasso, F., Cardini, M. (1988) Plasmacytoma of the parotid gland. Acta Oto-Rhino-Laryngologica Belgica 42: 9396.Google ScholarPubMed
Tesei, F., Caliceti, U., Sorrenti, G., Canciullo, A., Sabbatini, E., Pileri, S., Neri, S., Frezza, G., Rinaldi Ceroni, A. (1995) Extramedullary plasmacytoma of the head and neck: a series of 22 cases. Acta Otorhinolaryngologica Italiana 15: 437442.Google Scholar
Vainio-Mattila, J. (1965) Plasmacytoma of the parotid gland. Archives of Otolaryngology 82: 635637.CrossRefGoogle ScholarPubMed
Wax, M. K., Yun, K. J., Omar, R. A. (1993) Extramedullary plasmacytomas of the head and neck. Otolaryngology – Head and Neck Surgery 109: 877885.CrossRefGoogle ScholarPubMed
Wiltshaw, E. (1976) The natural history of extramedullary plasmacytoma and its relation to solitary myeloma of bone and myelomatosis. Medicine 55: 217238.CrossRefGoogle ScholarPubMed
Woodruff, R. K., Whittle, J. M., Malpas, J. S. (1979) Solitary plasmacytoma. Cancer 43: 23402343.3.0.CO;2-M>CrossRefGoogle ScholarPubMed