Hostname: page-component-586b7cd67f-g8jcs Total loading time: 0 Render date: 2024-11-30T23:32:34.606Z Has data issue: false hasContentIssue false

Premalignant changes in nasal and sinus polyps: a retrospective 10 year study (1979–1988)

Published online by Cambridge University Press:  29 June 2007

A. de la Cruzc Mera*
Affiliation:
Madrid, Spain
M. J. Sánchez López
Affiliation:
Madrid, Spain
E. Merino Royo
Affiliation:
Madrid, Spain
L. Requena
Affiliation:
Madrid, Spain
*
Capitan Medico D. Alberto del la Cruz Mera Servicio de Anatonia PatologicaHospital Militar Central “Gomez-Ulla”c/ Glorieta de Ejercito s/a28047, Madrid, Spain.

Abstract

One hundred and seventy cases of nasal and/or sinus polyps diagnosed in the Pathology Service of the Hospital Militar Central GOMEZ/ULLA of Madrid (Spain) between 1.9.79 and 1.9.88 are reviewed. In two cases areas of ‘carcinoma in situ’ in the epithelium covering the polyps were demonstrated. The literature is reviewed for reports of malignant transformation and dysplastic changes in nasal and sinusal polyps. We suggest that precancerous changes may ocassionally be noted in inflammatory lesions, a fact that pathologists should keep in mind.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 1990

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Badib, A. O., Kurohara, S. S., Webster, J. H. (1969) Treatment of cancer of the nasal cavity. American Journal of Roentgenology, 106: 824830.CrossRefGoogle ScholarPubMed
Barnes, L. (1985) Surgical pathology of the Head and Neck. Marcel Dekker Inc. New York.Google Scholar
Batsakis, J. G. (1979) Tumors of the Head and Neck. Williams and Wilkins, Baltimore.Google Scholar
Busutil, A. (1978) Dysplastic epithelial changes in nasal polyps. Annals of Otology, Rhinology and Laryngology, 87: 416420.CrossRefGoogle Scholar
Hasegawa, M., Nasu, M., Suginchi, Y., Watanabe, I. (1988) Malignant transformation of nasal polyp. Archives of Otolaryngology-Head and Neck Surgery, 114: 336337.CrossRefGoogle ScholarPubMed
Hyams, V. J. (1971) Papillomas of the nasal cavity and paranasal sinuses. A clinicopathologic study of 315 cases. Annals of Otology, Rhinology and Laryngology, 80: 192206.CrossRefGoogle ScholarPubMed
Kindblom, L. G., Angerwall, L. (1984) Nasal polyps with atypical stroma cells: A pseudosarcomatous lesion. A light and electron microcopsic and immunohistochemical investigation with implication on the type and nature of the mesenchymal cells. Acta Pathologica, Microbiologica et Inmunologica Scandinavica, 92: 6572.Google Scholar
Klenoff, B. H., Goodman, M. L. (1977) Mesenchymal cell atypicality in inflammatory polyps. Journal of Laryngology and Otology, 91: 751756.CrossRefGoogle ScholarPubMed
Lasser, A., Rothfeld, P. R., Shapiro, R. S. (1976) Epithelial papilloma and squamous cell carcinoma of the nasal cavity and paranasal sinuses. A clinicopathological study. Cancer, 38: 25032510.3.0.CO;2-S>CrossRefGoogle ScholarPubMed
Maran, A. G. D., Stell, P. M. (1981) Otorrinolaringologia clinica. Expaxs S. A. Barcelona (Spain), de la edicion original Clinical Otolaryngology, Blackwell Scientific publications England.Google Scholar
Perzin, K. M., Lefkowitch, J. H., Hui, R. M. (1981) Bilateral nasal squamous carcinoma arising in papillomatosis: Report of a case developing after chemotherapy for leukemia. Cancer, 48: 23752382.3.0.CO;2-L>CrossRefGoogle ScholarPubMed
Rubin, I. C. (1910) The pathologic diagnosis of incipient carcinoma of the uterus. American Journal of Obstetrics, 62: 668676.Google Scholar
Smith, C. J., Echevarria, R., McLelland, C. A. (1974) Pseudosarcomatous changes in antrochoanal polyps. Archives of Otolaryngology, 99: 228230.CrossRefGoogle ScholarPubMed
Snyder, R. N., Perzin, K. H. (1972) Papillomatosis of nasal cavity and paranasal sinuses (inverted papilloma, squamous papilloma). A clinicopathologic study. Cancer, 30: 668690.3.0.CO;2-B>CrossRefGoogle ScholarPubMed