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Multiple primary malignancies in patients with malignant tumours of the nasal cavities and paranasal sinuses

Published online by Cambridge University Press:  29 June 2007

Mamoru Miyaguchi ,
Shun-ichi Sakai ,
Nozomu Mori  and
Shigeo Kitaoku
Mamoru Miyaguchi*
Affiliation:
Kagawa, Japan
Shun-ichi Sakai
Affiliation:
Kagawa, Japan
Nozomu Mori
Affiliation:
Kagawa, Japan
Shigeo Kitaoku
Affiliation:
Kagawa, Japan
*
Dr Mamoru Miyaguchi, M.D., Department of Otolaryngology, Kagawa Medical School, 1750–1 Miki-cho Kita-gun, Kagawa 761–07, Japan
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Abstract

The incidence of multiple primary malignancies (MPM) was analysed in 1297 patients with malignant tumours of the nasal cavities and paranasal sinuses. The patients were followed for a minimum of six years or until death. The incidence of MPM was 3.4 per cent (44/1297) which is lower than in patients with malignant tumours of other regions in the upper aerodigestive tract. Five of the 44 patients had second malignancies within previously irradiated areas. There was a difference between the proportion of histologies occurring in irradiated tissues compared with the overall 1297 patients. This finding suggests that radiotherapy may induce a second cancer.

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 104 , Issue 9 , September 1990 , pp. 696 - 698
Copyright
Copyright © JLO (1984) Limited 1990

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