Hostname: page-component-cd9895bd7-gvvz8 Total loading time: 0 Render date: 2024-12-27T08:24:49.934Z Has data issue: false hasContentIssue false
  • English
  • Français

Malignant schwannoma arising in a paranasal sinus

Published online by Cambridge University Press:  29 June 2007

Ikuo Nagayama ,
Toshiro Nishimura  and
Mitsuru Furukawa
Ikuo Nagayama*
Affiliation:
(Kanazawa, Japan)
Toshiro Nishimura
Affiliation:
(Kanazawa, Japan)
Mitsuru Furukawa
Affiliation:
(Kanazawa, Japan)
*
Ikuo Nagayama, M.D., Department of Otolaryngology, School of Medicine, Kanazawa University, 13-1 Takaramachi, Kanazawashi, 920, Ishikawaken, Japan.
Get access Rights & Permissions [Opens in a new window]

Abstract

A case of malignant schwannoma arising in a paranasal sinus is reported. In this case, histological hallmarks were lost because of the poorly differentiated nature of the tumour. Immunohistological techniques were applied to the diagnosis, confirming the neural origin of this tumour. Malignant schwannoma is a relatively rare disease in the nasal cavity and paranasal sinuses. For the treatment of this tumour, wide resection is recommended. In this patient, radical resection of the maxilla with orbital and ethmoid exenteration was performed. The patient recovered uneventfully with no evidence of disease three years after surgery.

Keywords

Paranasal sinus neoplasmsmalignant schwannomaImmunohistochemistry
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 107 , Issue 2 , February 1993 , pp. 146 - 148
Copyright
Copyright © JLO (1984) Limited 1993

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bailet, J. W., Abemayor, E., Andrews, J. C, Rowland, J. P., Fu, Y. S., Dawson, D. D. (1991) Malignant nerve sheath tumors of the head and neck: a combined experience from two university hospitals. Laryngoscope, 101: 1044–1049.CrossRefGoogle ScholarPubMed
Das Guputa, T. K., Brasfield, R. D. (1970) Solitary malignant schwannoma. Annals of Surgery, 171: 419–428.CrossRefGoogle Scholar
Ghosh, B. C, Ghosh, L., Huvos, A. G., Former, J. G. (1973) Malignant schwannoma: a clinicopathologic study. Cancer, 31: 184–190.3.0.CO;2-8>CrossRefGoogle ScholarPubMed
Goepfert, H., Lindberg, R. D., Sinkovics, J. G., Ayala, A. G. (1977) Soft-tissue sarcoma of the head and neck. Archives of Otolaryngology, Head and Neck Surgery, 103: 365–368.CrossRefGoogle ScholarPubMed
Goldman, R. L., Jones, S. E., Heusinkvelo, R. S. (1977) Combination chemotherapy of metastatic malignant schwannoma with vincristine, adriamycin, cyclophosphamide and imidazole carboxamide. Cancer, 39: 1955–1958.3.0.CO;2-F>CrossRefGoogle ScholarPubMed
Gullane, P. J., Gilbert, R. W., van Nostrand, A. W. P. (1985) Malignant schwannoma of the head and neck. Journal of Otolaryngology, 14: 171–175.Google ScholarPubMed
Hoffman, D. F, Everts, E. C, Smith, J. D., Kyriakopoulos, D. D., Kessler, S. (1988) Malignant nerve sheath tumours of the head and neck. Otolaryngology—Head and Neck surgery, 99: 309–314.CrossRefGoogle Scholar
Hutcherson, R. W., Jenkins, H. A., Canalis, R. F., Handler, S. D., Eichel, B. S. (1979) Neurogenic sarcoma of the head and neck. Archives of Otolaryngology, Head and Neck Surgery, 105: 267–270.CrossRefGoogle ScholarPubMed
Marvel, J. B., Park, R. B. jr. (1990) Malignant schwannoma of the nasal cavity. Otolaryngology—Head and Neck Surgery, 102: 409–412.CrossRefGoogle ScholarPubMed
Nakajima, T., Kameya, T., Watanabe, S., Hirota, T., Sato, Y., Shimosato, Y. (1982) An immunoperoxidase study of S-100 protein distribution in normal and neoplastic tissues. American Journal of Surgical Pathology, 6: 715–727.CrossRefGoogle ScholarPubMed
Russel, W. O., Cohen, J., Enzinger, F., Hajdu, S. I., Heis, H., Martin, R. G., Meissner, W., Miller, W. T., Schmitz, R. L., Suit, H. D.(1977) A clinical and pathological staging system for soft tissue sarcomas. Cancer, 40: 1562–1570.3.0.CO;2-6>CrossRefGoogle Scholar
Sordillo, P. P., Helson, L., Hajdu, S. I., Margin, G. B., Kosloff, C., Golbey, R. B., Beattie, E. J. (1981) Malignant schwannoma–clinical characteristics, survival and response to therapy. Cancer, 47: 2503–2509.3.0.CO;2-3>CrossRefGoogle ScholarPubMed
Stefansson, K., Wollmann, R., Jorkovic, M. (1982) S-100 protein in soft-tissue tumors derived from schwann cells and melanocytes. American Journal of Pathology, 106: 261– 268.Google ScholarPubMed
Trojanwski, J. Q., Kleinman, G. M., Proppe, K. H. (1980) Malignant tumors of nerve sheath origin. Cancer, 46: 1202–1212.3.0.CO;2-5>CrossRefGoogle Scholar
Vieta, J. O., Peck, G. T. (1951) Malignant neurilemomas of peripheral nerves. American Journal of Surgery, 82: 416–431.CrossRefGoogle Scholar
White, H. R. (1971) Survival in malignant schwannoma: an 18-year study. Cancer, 27: 720–729.3.0.CO;2-D>CrossRefGoogle ScholarPubMed