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Macrocytosis and sudden sensorineural hearing loss: a case report

Published online by Cambridge University Press:  23 September 2015

A E L McMurran*
Affiliation:
Department of Otolaryngology, Ulster Hospital, Belfast, Northern Ireland, UK
R A Adair
Affiliation:
Department of Otolaryngology, Ulster Hospital, Belfast, Northern Ireland, UK
*
Address for correspondence: Ms A E L McMurran, Department of Otolaryngology, Ulster Hospital, Upper Newtownards Road, Dundonald, Belfast BT16 1RH, Northern Ireland, UK E-mail: [email protected]

Abstract

Background:

Although other blood dyscrasias are known to cause sudden sensorineural hearing loss, macrocytosis has not previously been implicated in the absence of another causative agent.

Case report:

We present a case of bilateral sequential sudden sensorineural hearing loss in a patient with significant macrocytosis (mean corpuscular volume at presentation 124 fl) secondary to alcohol-induced liver dysfunction.

Conclusion:

A possible pathophysiological mechanism linking macrocytosis and sudden sensorineural hearing loss was identified, suggesting areas for further investigation.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 2015 

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Footnotes

Presented as an oral presentation at the Royal Academy of Medicine in Ireland Otolaryngology Winter Meeting, 12 December 2014, Dublin, Ireland

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