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Lateral temporal bone resection for cutaneous carcinomas of the external auditory canal and peri-auricular region

Published online by Cambridge University Press:  29 September 2021

S Leedman ,
R Wormald  and
S Flukes
S Leedman*
Affiliation:
Department of Otolaryngology Head and Neck Surgery, Fiona Stanley Hospital, Perth, Australia
R Wormald
Affiliation:
Department of Otolaryngology Head and Neck Surgery, Fiona Stanley Hospital, Perth, Australia
S Flukes
Affiliation:
Department of Otolaryngology Head and Neck Surgery, Fiona Stanley Hospital, Perth, Australia
*
Author for correspondence: Dr Samuel Leedman, Department of Otolaryngology Head and Neck Surgery, Fiona Stanley Hospital, 11 Robin Warren Drive, MurdochWA, Australia6150 E-mail: [email protected]
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Abstract

Objectives

To evaluate the outcomes for patients after lateral temporal bone resection surgery for cutaneous squamous cell carcinoma and basal cell carcinoma, and to ascertain predictors of survival and treatment failure.

Methods

A retrospective review was conducted of the medical records for all patients who underwent lateral temporal bone resection for cutaneous squamous cell carcinoma or basal cell carcinoma between 2007 and 2019 in Western Australia.

Results

Thirty-seven patients underwent lateral temporal bone resection surgery. Median follow-up duration was 22 months. Twenty-five patients had squamous cell carcinoma and 12 had basal cell carcinoma. The overall survival rate at two years for patients with squamous cell carcinoma was 68.5 per cent. Pre-operative facial nerve involvement (determined via clinical or radiological evidence) was identified as a predictor of mortality (hazard ratio = 3.411, p = 0.006), with all patients dying before two years post-operatively. Locoregional tumour control was achieved in 81 per cent of cases (n = 30).

Conclusion

Lateral temporal bone resection offers acceptable local control rates and survival outcomes. Caution should be used in offering this surgery to patients with clinical or radiological evidence of facial nerve involvement because of the relatively poorer survival outcomes in this subgroup.

Keywords

Temporal BoneSkin NeoplasmsSkin Cancer
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 135 , Issue 12 , December 2021 , pp. 1057 - 1062
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press

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Footnotes

Dr S Leedman takes responsibility for the integrity of the content of the paper

References

Lobo, D, Llorente, JL, Suarez, C. Squamous cell carcinoma of the external auditory canal. Skull Base 2008;18:167–72CrossRefGoogle ScholarPubMed
Seligman, KL, Sun, DQ, Ten Eyck, PP, Schularick, NM, Hansen, MR. Temporal bone carcinoma: treatment patterns and survival. Laryngoscope 2020;130:E11–20CrossRefGoogle ScholarPubMed
Gurgel, RK, Karnell, LH, Hansen, MR. Middle ear cancer: a population-based study. Laryngoscope 2009;119:1913–17CrossRefGoogle ScholarPubMed
Madsen, AR, Gundgaard, MG, Hoff, CM, Maare, C, Holmboe, P, Knap, M et al. Cancer of the external auditory canal and middle ear in Denmark from 1992 to 2001. Head Neck 2008;30:1332–8CrossRefGoogle ScholarPubMed
Shen, W, Sakamoto, N, Yang, L. Prognostic models to predict overall and cause-specific survival for patients with middle ear cancer: a population-based analysis. BMC Cancer 2014;14:554CrossRefGoogle ScholarPubMed
Charlson, ME, Pompei, P, Ales, KL, MacKenzie, CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987;40:373–83CrossRefGoogle ScholarPubMed
Amin, M, Edge, S, Greene, F, Byrd, D, Brookland, R, Washington, M et al. AJCC Cancer Staging Manual, 8th edn. New York: Springer International Publishing, 2017CrossRefGoogle ScholarPubMed
Dindo, D, Demartines, N, Clavien, PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 2004;240:205–13CrossRefGoogle Scholar
Pfreundner, L, Schwager, K, Willner, J, Baier, K, Bratengeier, K, Brunner, FX et al. Carcinoma of the external auditory canal and middle ear. Int J Radiat Oncol Biol Phys 1999;44:777–88CrossRefGoogle ScholarPubMed
Essig, GF, Kitipornchai, L, Adams, F, Zarate, D, Gandhi, M, Porceddu, S et al. Lateral temporal bone resection in advanced cutaneous squamous cell carcinoma: report of 35 patients. J Neurol Surg B Skull Base 2013;74:54–9Google ScholarPubMed
Shiga, K, Ogawa, T, Maki, A, Amano, M, Kobayashi, T. Concomitant chemoradiotherapy as a standard treatment for squamous cell carcinoma of the temporal bone. Skull Base 2011;21:153–8CrossRefGoogle ScholarPubMed
Morita, S, Homma, A, Nakamaru, Y, Sakashita, T, Hatakeyama, H, Kano, S et al. The outcomes of surgery and chemoradiotherapy for temporal bone cancer. Otol Neurotol 2016;37:1174–82CrossRefGoogle ScholarPubMed
Takenaka, Y, Cho, H, Nakahara, S, Yamamoto, Y, Yasui, T, Inohara, H. Chemoradiation therapy for squamous cell carcinoma of the external auditory canal: a meta-analysis. Head Neck 2015;37:1073–80CrossRefGoogle ScholarPubMed
Shinomiya, H, Hasegawa, S, Yamashita, D, Ejima, Y, Kenji, Y, Otsuki, N et al. Concomitant chemoradiotherapy for advanced squamous cell carcinoma of the temporal bone. Head Neck 2016;38(suppl 1):E949–53CrossRefGoogle ScholarPubMed
Dean, NR, White, HN, Carter, DS, Desmond, RA, Carroll, WR, McGrew, BM et al. Outcomes following temporal bone resection. Laryngoscope 2010;120:1516–22CrossRefGoogle ScholarPubMed
Ducic, Y, Miles, BA, Sabatini, P. Extending the traditional resection limits of squamous cell carcinoma of the anterior skull base. Otolaryngol Head Neck Surg 2007;137:899–905CrossRefGoogle ScholarPubMed
Gidley, PW, Thompson, CR, Roberts, DB, DeMonte, F, Hanna, EY. The oncology of otology. Laryngoscope 2012;122:393–400CrossRefGoogle ScholarPubMed
Moore, MG, Deschler, DG, McKenna, MJ, Varvares, MA, Lin, DT. Management outcomes following lateral temporal bone resection for ear and temporal bone malignancies. Otolaryngol Head Neck Surg 2007;137:893–8CrossRefGoogle ScholarPubMed
Gidley, PW, Roberts, DB, Sturgis, EM. Squamous cell carcinoma of the temporal bone. Laryngoscope 2010;120:1144–51Google ScholarPubMed
Gandhi, AK, Roy, S, Biswas, A, Raza, MW, Saxena, T, Bhasker, S et al. Treatment of squamous cell carcinoma of external auditory canal: a tertiary cancer centre experience. Auris Nasus Larynx 2016;43:45–9CrossRefGoogle ScholarPubMed
Leong, SC, Youssef, A, Lesser, TH. Squamous cell carcinoma of the temporal bone: outcomes of radical surgery and postoperative radiotherapy. Laryngoscope 2013;123:2442–8Google ScholarPubMed
Gidley, PW, Thompson, CR, Roberts, DB, Weber, RS. The results of temporal bone surgery for advanced or recurrent tumors of the parotid gland. Laryngoscope 2011;121:1702–7CrossRefGoogle ScholarPubMed
Shao, A, Wong, DK, McIvor, NP, Mylnarek, AM, Chaplin, JM, Izzard, ME et al. Parotid metastatic disease from cutaneous squamous cell carcinoma: prognostic role of facial nerve sacrifice, lateral temporal bone resection, immune status and P-stage. Head Neck 2014;36:545–50CrossRefGoogle ScholarPubMed
Nader, ME, Ginsberg, LE, Bell, D, Roberts, DB, Gidley, PW. Evaluating perineural spread to the intratemporal facial nerve on magnetic resonance imaging. Otolaryngol Head Neck Surg 2019;160:1087–94CrossRefGoogle ScholarPubMed
Gandhi, MR, Panizza, B, Kennedy, D. Detecting and defining the anatomic extent of large nerve perineural spread of malignancy: comparing “targeted” MRI with the histologic findings following surgery. Head Neck 2011;33:469–75CrossRefGoogle ScholarPubMed