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Laryngeal carcinoma metastasis to the orbit: case report

Published online by Cambridge University Press:  27 January 2011

T Galm*
Affiliation:
Department of ENT, Heartlands Hospital, Birmingham, UK
A Kulkarni
Affiliation:
Department of Ophthalmology, Heartlands Hospital, Birmingham, UK
I Ahmad
Affiliation:
Department of ENT, Heartlands Hospital, Birmingham, UK
*
Address for correspondence: Ms T Galm, Heartlands Hospital, Bordesley Green, Birmingham B9 5ST, UK E-mail: [email protected]

Abstract

Objective:

We present the first report in the all English literature of a case of laryngeal squamous cell carcinoma metastasis to the orbit.

Method:

Case report of orbital metastasis from laryngeal carcinoma; clinical, radiological and pathological findings are discussed.

Result:

A 75-year-old man presented to the ENT department with a five-week history of left orbital pain, swelling and reduced vision. Past medical history included laryngectomy, bilateral neck dissection and post-operative radiotherapy for T4 N2c M0 squamous cell carcinoma of the supraglottis, 10 months earlier. Imaging showed an orbital mass extending along the roof and lateral aspect of the orbit into the optic canal and superior orbital fissure, and further posteriorly into the left cavernous sinus with meningeal enhancement in the left anterior cranial fossa. Histopathological analysis after biopsy showed the mass to be consistent with metastatic poorly differentiated squamous cell carcinoma.

Conclusion:

After searching the all English literature, we report what is, to our best knowledge, the first case of laryngeal carcinoma metastasis to the orbit. Despite its rarity and poor prognosis, such a metastasis should be considered as part of the differential diagnosis of an orbital mass, as timely recognition can improve the patient's quality of life.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 2011

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References

1Garavello, W, Ciardo, A, Spreafico, R, Gaini, RM. Risk factors for distant metastases in head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 2006;132:762–6CrossRefGoogle ScholarPubMed
2Spector, GJ. Distant metastases from laryngeal and hypopharyngeal cancer. ORL J Otorhinolaryngol Relat Spec 2001;64:224–8CrossRefGoogle Scholar
3Spector, GJ, Sessions, DG, Haughey, BH, Chas, KS, Simpson, J, El Mofty, S. Delayed regional metastasis, distance metastasis and second primary malignancies in squamous cell carcinomas of the larynx and hypopharynx. Laryngoscope 2001;111:1079–87CrossRefGoogle Scholar
4Korkmaz, H, Dursan, E, Saylam, G, Akmansu, M, Eryilmaz, A. An unusual metastatic pattern of larynx cancer: the forearm. KBB-forum 2007 www.KBB-Forum.netGoogle Scholar
5Yucel, EA, Demirel, T, Demiryont, M, Egeli, U, Deger, K. An unusual metastatic site of laryngeal carcinoma: scapular muscle. J Laryngol Otol 2003;117:85–7CrossRefGoogle Scholar
6Marioni, G, Blandamura, S, Calgaro, N, Ferraro, SM, Stramare, R, Staffieri, A et al. Distant muscular (gluteus maximus muscle) metastasis from laryngeal squamous cell carcinoma. Acta Otolaryngol 2005;125:678–82CrossRefGoogle ScholarPubMed
7Buyukcelik, A, Ensari, A, Sarioglu, M, Isikdogan, A, Icli, F. Squamous cell carcinoma of the larynx metastasized to the ampulla of vater: report of a case. Tumori 2003;89:199201CrossRefGoogle Scholar
8Horner, F. Carcinoma of the dura mater. Exophthalmos-Carcinoma of the rectus muscle. General Carcinoma [in German]. Klin Monartsble Augenheilkd 1864;2:186–90Google Scholar
9Srinivasan, R, Krishnanand, G. Cytologic diagnosis of metastatic hepatocellular carcinoma presenting as an orbital mass. A case report. Acta Cytol 2007;51:83–5CrossRefGoogle ScholarPubMed
10Rosenberg, C, Finger, PT. Cutaneous malignant melanoma metastatic to the eye, lid and orbit. Surv Ophthalmol 2008:53;187202CrossRefGoogle Scholar
11Shome, D, Honavar, SG, Gupta, P, Vemuganti, GK, Reddy, PV. Metastasis to the eye and orbit from renal cell carcinoma: a report of three cases and review of literature. Surv Ophthalmol 2007;52:213–23CrossRefGoogle Scholar
12Goldberg, RA, Rootman, J, Cline, RA. Tumours metastastic to the orbit. A changing picture. Surv Ophthalmol 1990;35:123CrossRefGoogle Scholar
13Saleh, HA. A case of prostatic cancer metastatic to the orbit and ethmoid sinus. Ann Otol Rhinol Laryngol 1996;584:105–7Google Scholar
14Aspraudis, I, Garezis, S, Konstantines, C, Stefaniotau, M. Breast carcinoma metastasis to the orbit and paranasal sinuses: a case report. Exp Oncol 2004;26:246–8Google Scholar
15Wang, Y, Yang, XJ, Li, YY, Hei, Y, Xiao, LH. Diagnosis and management of orbital metastatic tumors [in Chinese]. Zhonghua YanKe ZaZhi 2008;44:687–90Google ScholarPubMed
16Font, RL, Ferry, AP. Carcinoma metastatic to the eye and orbit. A clinicopathologic study of 28 cases metastatic to the orbit. Cancer 1976;38:1326–353.0.CO;2-#>CrossRefGoogle Scholar
17Valenzuela, AA, Archibald, CW, Fleming, B, Ong, L, O'Donnell, B, Crompton, J et al. Orbital metastasis: clinical features, management and outcome. Orbit 2009;28:153–9CrossRefGoogle ScholarPubMed
18Huh, S, Nisce, LZ, Simpson, LD. Value of radiation therapy in the treatment of orbital metastasis. Am J Roentgenol 1974;120:589–61CrossRefGoogle ScholarPubMed