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kikuchi–Fujimoto disease: a report of two cases and an overview

Published online by Cambridge University Press:  29 June 2007

N. Louis ,
M. Hanley  and
N. McD. Davidson
N. Louis*
Affiliation:
Departments of Surgery, North-West Armed Forces Hospital, PO Box 100, Tabuk, Saudi Arabia.
M. Hanley
Affiliation:
Departments of Surgery, North-West Armed Forces Hospital, PO Box 100, Tabuk, Saudi Arabia.
N. McD. Davidson
Affiliation:
Departments of Pathology and Internal Medicine, North-West Armed Forces Hospital, PO Box 100, Tabuk, Saudi Arabia.
*
Dr N. Louis, Senior Consultant ENT Surgeon, Department of Surgery, NWAF Hospital, PO Box 100, Tabuk, Saudi Arabia. Fax: 966–4–423–2795
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Abstract

Kikuchi-Fujimoto disease (KFD) has been widely reported from Japan and sporadically from many parts of the world including Saudi Arabia, since its original description in 1972 but the disease remains poorly known by clinicians. In this paper we report two Saudi patients seen in Tabuk. Saudi Arabia. One was a 36-year-old Saudi man and the other a 16-yearold Saudi girl. Both presented with cervical lymphadenopathy and pyrexia. Histological examination of biospy material from both showed classical features of KFD. Other laboratory findings were unremarkable except for leucopenia. Following excision biopsy both patients recovered without sequelae. KFD is a self-limiting process of uncertain aetiology that predominantly affects young women aged 20–-30 years. We review the pathology, clinical featuers and possible aetiology of this interesting disease, which may well be underdiagnosed. Increased awareness of KFD will minimize the risk of confusing this entity with malignant lymphoma or other serious conditions.

Keywords

Lymphadenitisnecrotizing histiocytic
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 108 , Issue 11 , November 1994 , pp. 1001 - 1004
Copyright
Copyright © JLO (1984) Limited 1994

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