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Intranasal myopericytoma. A tumour with perivascular myoid differentiation: the changing nomenclature for haemangiopericytoma

Published online by Cambridge University Press:  10 April 2007

T Wilson ,
H B Hellquist ,
S Ray  and
J Pickles
T Wilson*
Affiliation:
ENT Department, James Paget Hospital, Great Yarmouth, Norfolk, UK
H B Hellquist
Affiliation:
Department of Cellular Pathology, Norfolk & Norwich University Hospital, Norwich, UK
S Ray
Affiliation:
ENT Department, Luton & Dunstable Hospital, Luton, UK.
J Pickles
Affiliation:
ENT Department, Luton & Dunstable Hospital, Luton, UK.
*
Address for correspondence: Mr T Wilson, 73 Norfolk Street, Cambridge CB1 2LD, UK. E-mail: [email protected]
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Abstract

We present a case report of a patient who developed a sinonasal myopericytoma treated by surgical excision through a lateral rhinotomy. Some aggressive features on pre-operative computed tomography scanning and the complexity of recent changes in the histological nomenclature for these tumours led to consideration of adjuvant therapy. The close histological relationship between myopericytoma, myofibromatosis, solitary myofibroma and infantile haemangiopericytoma is discussed. This group of lesions constitute a single morphological spectrum with differentiation towards perivascular myoid cells (pericytes). Currently myopericytoma is the most appropriate and accepted term embracing all these entities. A review of the literature has been reassuring in identifying these tumours as benign but with a reasonably high rate of local recurrence (17 per cent). The treatment of choice is surgical excision with further excisions for local recurrence.

Keywords

HistopathologyImmunohistochemistryGlomus TumourParanasal Sinus NeoplasmsRecurrenceSurgeryTerminology
Type
Short Communications
Information
The Journal of Laryngology & Otology , Volume 121 , Issue 8 , August 2007 , pp. 786 - 789
Copyright
Copyright © JLO (1984) Limited 2007

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References

1Granter, SR, Badizadegan, K, Fletcher, CD. Myofibromatosis in adults, glomangiopericytoma, and myopericytoma: A spectrum of tumors showing perivascular myoid differentiation. Am J Surg Pathol 1998;22:513–25CrossRefGoogle ScholarPubMed
2Calonje, E, Fletcher, CDM. Tumors of blood vessels and lymphatics. In: Fletcher, CDMDiagnostic histopathology of tumors, 2nd edn. London: Edinburgh, New York, Churchill Livingstone, 2000;45–86Google Scholar
3Stout, AP, Murray, MR. Hemangiopericytoma: a vascular tumor featuring Zimmermann's pericytes. Ann Surg 1942;116:26–33CrossRefGoogle ScholarPubMed
4Requena, L, Kutzner, H, Hugel, H, Rutten, A, Furio, V. Cutaneous adult myofibroma: a vascular neoplasm. J Cutan Pathol 1996;23:445–57CrossRefGoogle ScholarPubMed
5Thompson, LD, Miettinen, M, Wenig, BM. Sinonasal-type hemangiopericytoma. A clinicopathologic and immunophenotypic analysis of 104 cases showing perivascular myoid differentiation. Am J Surg Pathol 2003;27:737–49CrossRefGoogle ScholarPubMed
6Barnes, L. Hemangiopericytoma. In: Barnes, L, ed. Surgical Pathology of the Head and Neck. New York: Marcel Decker, 2002;986–91Google Scholar
7Eichhorn, JH, Dickersin, GR, Bhan, AK, Goodman, ML. Sinonasal hemangiopericytoma. A reassessment with electron microscopy, immunohistochemistry, and long-term follow-up. Am J Surg Pathol 1990;14:856–66CrossRefGoogle ScholarPubMed
8Backwinkel, KD, Diddams, JA. Hemangiopericytoma. Report of a case and comprehensive review of the literature. Cancer 1970;25:896–9013.0.CO;2-N>CrossRefGoogle ScholarPubMed
9Mentzel, T, Hugel, H, Kutzner, H. CD34-positive glomus tumor: clinicopathologic and immunohistochemical analysis of six cases with myxoid stromal changes. J Cutan Pathol 2002;29:421–5CrossRefGoogle ScholarPubMed
10McMenamin, ME, Fletcher, CD. Malignant myopericytoma: expanding the spectrum of tumours with myopericytic differentiation. Histopathology 2002;41:450–60CrossRefGoogle ScholarPubMed
11Tse, LL, Chan, JK. Sinonasal haemangiopericytoma-like tumour: a sinonasal glomus tumour or a haemangiopericytoma. Histopathology 2001;40:510–17CrossRefGoogle Scholar