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Interarytenoid botulinum toxin A injection for the treatment of vocal process granuloma

Published online by Cambridge University Press:  12 November 2019

A-L Hamdan ,
E Khalifee ,
H Jaffal  and
A Ghanem
A-L Hamdan*
Affiliation:
Department of Otorhinolaryngology Head and Neck Surgery, American University of Beirut Medical Center, Lebanon
E Khalifee
Affiliation:
Department of Otorhinolaryngology Head and Neck Surgery, American University of Beirut Medical Center, Lebanon
H Jaffal
Affiliation:
Department of Otorhinolaryngology Head and Neck Surgery, American University of Beirut Medical Center, Lebanon
A Ghanem
Affiliation:
Department of Otorhinolaryngology Head and Neck Surgery, American University of Beirut Medical Center, Lebanon
*
Author for correspondence: Dr Abdul-Latif Hamdan, Department of Otolaryngology Head and Neck Surgery, American University of Beirut Medical Center, PO Box 11-0236, Beirut, Lebanon E-mail: [email protected] Fax: +961 1 350 000
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Abstract

Objectives

To report on the efficacy and adverse effects of interarytenoid botulinum toxin A injection for the treatment of vocal process granuloma.

Methods

A retrospective chart review was conducted of eight patients with vocal process granuloma resistant to anti-reflux therapy who underwent interarytenoid botulinum toxin A injection. The mean dosage of botulinum toxin A injected was 6.56 U.

Results

Fifty per cent of patients had complete regression of the lesion and 50 per cent had partial regression. The main side effects were breathiness (n = 4), voice breaks (n = 1) and aspiration (n = 1).

Conclusion

Interarytenoid botulinum toxin A injection for the treatment of vocal process granuloma is an effective mode of therapy, with transient vocal and swallowing side effects.

Keywords

VoiceGranulomaInjectionsBotulinum Toxin
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 133 , Issue 12 , December 2019 , pp. 1041 - 1045
Copyright
Copyright © JLO (1984) Limited, 2019

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Footnotes

Dr A-L Hamdan takes responsibility for the integrity of the content of the paper

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