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Immunocytochemical identification of HIV (p24) antigen in parotid lymphoid lesions

Published online by Cambridge University Press:  29 June 2007

J. M. Bruner
Affiliation:
Department of Pathology, The University of Texas MD., Anderson Cancer Center at Houston
K. R. Cleary
Affiliation:
Department of Pathology, The University of Texas MD., Anderson Cancer Center at Houston
F. B. Smith
Affiliation:
Department of Pathology, St. Vincent's Hospital, New York, New York.
J. G. Batsakis*
Affiliation:
Department of Pathology, The University of Texas MD., Anderson Cancer Center at Houston
*
John G. Batsakis, MD, Department of Pathology, The University of Texas MD, Anderson Cancer Center, 1515 Holcombe Blvd, Houston, Texas (713) 793-3100

Abstract

Antibodies to specific human immunodeficiency virus (HIV) polypeptides are important laboratory markers of HIV infection. We have used an antibody to the major structural gag protein p24 of HIV-1 virus to immunochemically localize this capsid antigen in lymphoid cells from seven of eight patients at risk for HIV infection and who presented with parotid lymphadenopathy and lymphoepithelial cysts of the parotid gland. A clinicopathological assessment of these two manifestations as they relate to HIV infection is also presented.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 1989

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