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Hydralazine-induced lupus and vocal fold paralysis

Published online by Cambridge University Press:  29 June 2007

C. K. Hari ,
S. Ali Raza  and
M. I. Clayton
C. K. Hari*
Affiliation:
Department of Otolaryngology and Head and Neck Surgery, Royal Gwent Hospital, Newport, U.K.
S. Ali Raza
Affiliation:
Department of Otolaryngology and Head and Neck Surgery, Royal Gwent Hospital, Newport, U.K.
M. I. Clayton
Affiliation:
Department of Otolaryngology and Head and Neck Surgery, Royal Gwent Hospital, Newport, U.K.
*
Address for correspondence: Mr C. K. Hari, F.R.C.S., Department of Otolaryngology and Head and Neck Surgery, Royal Gwent Hospital, Newport NP9 2UB. Fax: (01633) 238123
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Abstract

Systemic lupus erythematosus (SLE) is a multi-system autoimmune disorder that can affect the upper airway. Hydralazine has been known to cause a lupus-like syndrome that can produce the clinical manifestations of SLE. We discuss a case of hydralazine-induced lupus, presenting with acute laryngeal oedema and right vocal fold paralysis. Cessation of hydralazine therapy resulted in reversal of paralysis.

Keywords

Lupus erythematosus, systemicVocal fold paralysisHydralazine
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 112 , Issue 9 , September 1998 , pp. 875 - 877
Copyright
Copyright © JLO (1984) Limited 1998

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