Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-24T07:03:19.220Z Has data issue: false hasContentIssue false
  • English
  • Français

Hearing loss in patients with Behçet's disease: an audiological and transient evoked otoacoustic emission study

Published online by Cambridge University Press:  29 September 2009

S Aslan ,
G Serarslan ,
N Savas ,
E Teksoz  and
S Dagli
S Aslan*
Affiliation:
Department of Otorhinolaryngology, Faculty of Medicine, Mustafa Kemal University, Hatay, Turkey
G Serarslan
Affiliation:
Department of Dermatology, Faculty of Medicine, Mustafa Kemal University, Hatay, Turkey
N Savas
Affiliation:
Department of Public Health, Faculty of Medicine, Mustafa Kemal University, Hatay, Turkey
E Teksoz
Affiliation:
Antakya Maternity Hospital, Hatay, Turkey
S Dagli
Affiliation:
Department of Otorhinolaryngology, Faculty of Medicine, Mustafa Kemal University, Hatay, Turkey
*
Address for correspondence: Dr Sundus Aslan, Ürgen Paşa Mh 75 yıl Bulv, Ceren Apt No 6/19, 31040 Antakya, Hatay, Turkey. Fax: +90 326 214 49 77 E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective:

To investigate hearing loss in patients with Behçet's disease.

Materials and methods:

Twenty-four consecutive cases of Behçet's disease and 24 sex- and age-matched controls were included in this study. Pure tone and high frequency audiometric tests were performed and pure tone average hearing thresholds calculated for both groups. Transient evoked otoacoustic emission testing was also performed.

Results:

Pure tone audiometry showed a sensorineural hearing loss in 15 of the Behçet's disease ears. Hearing thresholds were significantly higher in the study group than in the control group, on both pure tone frequency (except 0.5 kHz) and high frequency audiometry. Significant reductions in transient evoked otoacoustic emission amplitude were found at 1.4 and 2 kHz in the Behçet's disease patients. There were no significant differences in reproducibility, stimulus intensity or stability, comparing the Behçet's disease patients and controls.

Conclusion:

Significantly lower mid-frequency amplitudes were found in Behçet's patients on transient evoked otoacoustic emission testing.

Keywords

Behçet's DiseaseOtoacoustic EmissionHearing Loss
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 124 , Issue 1 , January 2010 , pp. 10 - 15
Copyright
Copyright © JLO (1984) Limited 2009

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1 Onder, M, Gürer, MA. The multiple faces of Behçet's disease and its aetiological factors. J Eur Acad Dermatol Venereol 2001;15:126–36CrossRefGoogle ScholarPubMed
2 Reynolds, N. Vasculitis in Behçet's syndrome: evidence-based review. Curr Opin Rheumatol 2008;20:347–52CrossRefGoogle ScholarPubMed
3 Zierhut, M, Mizuki, N, Ohno, S, Inoko, H, Gül, A, Onoé, K et al. Immunology and functional genomics of Behçet's disease. Cell Mol Life Sci 2003;60:1903–22CrossRefGoogle ScholarPubMed
4 Rizzi, R, Bruno, S, Dammacco, R. Behçet's disease: an immune-mediated vasculitis involving vessels of all sizes. Int J Clin Lab Res 1997;27:225–32CrossRefGoogle ScholarPubMed
5 Soylu, L, Aydoğan, B, Soylu, M, Ozsahinoğlu, C. Hearing loss in Behçet's disease. Ann Otol Rhinol Laryngol 1995;104:864–7CrossRefGoogle ScholarPubMed
6 Ak, E, Harputluoglu, U, Oghan, F, Baykal, B. Behçet's disease and hearing loss. Auris Nasus Larynx 2004;31:29–33CrossRefGoogle ScholarPubMed
7 Muluk, NB, Birol, A. Effects of Behçet's disease on hearing thresholds and transient evoked otoacoustic emissions. J Otolaryngol 2007;36:220–6CrossRefGoogle ScholarPubMed
8 Bayazit, YA, Yilmaz, M, Gunduz, B, Altinyay, S, Kemaloglu, YK, Onder, M et al. Distortion product otoacoustic emission findings in Behçet's disease and rheumatoid arthritis. ORL J Otorhinolaryngol Relat Spec 2007;69:233–8CrossRefGoogle ScholarPubMed
9 Dagli, M, Eryilmaz, A, Tanrikulu, S, Aydin, A, Gonul, M, Gul, U et al. Evaluation of cochlear involvement by distortion product otoacoustic emission in Behçet's disease. Auris Nasus Larynx 2008;35:333–7CrossRefGoogle ScholarPubMed
10 Kemp, DT. Otoacoustic emissions, their origin in cochlear function, and use. Br Med Bull 2002;63:223–41CrossRefGoogle Scholar
11 Probst, R, Lonsbury-Martin, BL, Martin, GK. A review of otoacoustic emissions. J Acoust Soc Am 1991;89:2027–67CrossRefGoogle ScholarPubMed
12 Criteria for diagnosis of Behçet's disease. International Study Group for Behçet's Disease. Lancet 1990;335:1078–80Google Scholar
13 Yilmaz, I, Yilmazer, C, Erkan, AN, Aslan, SG, Ozluoglu, LN. Intratympanic dexamethasone injection effects on transient-evoked otoacoustic emission. Am J Otolaryngol 2005;26:113–17CrossRefGoogle ScholarPubMed
14 Yeo, SW, Park, SN, Park, YS, Suh, BD. Effect of middle-ear effusion on otoacoustic emissions. J Laryngol Otol 2002;116:794–9CrossRefGoogle ScholarPubMed
15 Ravazzani, P, Tognola, G, Sergi, P, Pastorino, GC, Grandori, F. Analysis of spontaneous and click-evoked otoacoustic emissions in newborns. Scand Audiol Suppl 2001;52:133–4CrossRefGoogle Scholar
16 Namyslowski, G, Morawski, K, Urbaniec, N, Lisowska, G, Trybalska, G, Bazowska, G et al. The hearing system in newborns from the Upper Silesia. Assessment of TEOAE depending on selected parameters of delivery disorders. Scand Audiol Suppl 2001;52:21–4CrossRefGoogle Scholar
17 Chapchap, MJ, Segre, CM. Universal newborn hearing screening and transient evoked otoacoustic emission: new concepts in Brazil. Scand Audiol Suppl 2001;53:33–6CrossRefGoogle Scholar
18 Chang, KW, Vohr, BR, Norton, SJ, Lekas, MD. External and middle ear status related to evoked otoacoustic emission in neonates. Arch Otolaryngol Head Neck Surg 1993;119:276–82CrossRefGoogle ScholarPubMed
19 Grandori, F, Sergi, P, Pastorino, G, Uloziene, I, Calo, G, Ravazzani, P et al. Comparison of two methods of TEOAE recording in newborn hearing screening. Int J Audiol 2002;41:267–70CrossRefGoogle ScholarPubMed
20 Chang, SO, Jang, YJ, Rhee, CK. Effects of middle ear effusion on transient evoked otoacoustic emissions in children. Auris Nasus Larynx 1998;25:243–7CrossRefGoogle ScholarPubMed
21 Lalaki, P, Markou, K, Tsalighopoulos, MG, Daniilidis, I. Transiently evoked otoacoustic emissions as a prognostic indicator in idiopathic sudden hearing loss. Scand Audiol Suppl 2001;52:141–5CrossRefGoogle Scholar
22 The International Study Group for Behçet's disease. Evaluation of diagnostic (‘classification’) criteria in Behçet's disease – towards internationally agreed criteria. Br J Rheumatol 1992;31:299–308CrossRefGoogle Scholar
23 Andreoli, C, Savastano, M. Audiologic pathology in Behçet syndrome. Am J Otol 1989;10:466–7Google ScholarPubMed
24 Arts, HA. Sensorineural hearing loss: evaluation and management in adults. In: Cummings, CW, Flint, PW, Harker, LA, Haughey, BH, Richardson, MA, Robbins, KT et al. , eds. Cummings Otolaryngology-Head and Neck Surgery, 4th edn. Philadelphia: Mosby, 2005;3535–61Google Scholar
25 Elidan, J, Levi, H, Cohen, E, BenEzra, D. Effect of cyclosporine A on the hearing loss in Behçet's disease. Ann Otol Rhinol Laryngol 1991;100:464–8CrossRefGoogle ScholarPubMed
26 Gemignani, G, Berrettini, S, Bruschini, P, Sellari-Franceschini, S, Fusari, P, Piragine, F et al. Hearing and vestibular disturbances in Behçet's syndrome. Ann Otol Rhinol Laryngol 1991;100:459–63CrossRefGoogle ScholarPubMed
27 Pollak, L, Luxon, LM, Haskard, DO. Labyrinthine involvement in Behçet's syndrome. J Laryngol Otol 2001;115:522–9CrossRefGoogle ScholarPubMed
28 Kulahli, I, Balci, K, Koseoglu, E, Yuce, I, Cagli, S, Senturk, M. Audio-vestibular disturbances in Behcet's patients: report of 62 cases. Hear Res 2005;203:28–31CrossRefGoogle ScholarPubMed