Hostname: page-component-cd9895bd7-gxg78 Total loading time: 0 Render date: 2024-12-28T17:42:01.712Z Has data issue: false hasContentIssue false
  • English
  • Français

Hearing loss in multiple sclerosis: localization of the auditory pathway lesion according to electrocochleographic findings

Published online by Cambridge University Press:  29 June 2007

N. Marangos
N. Marangos*
Affiliation:
HNO-Klinik, Albert-Ludwigs-Universität Freiburg, Germany.
*
Address for correspondence: Dr Med. N. Marangos, HNO-Klinik, Albert-Ludwigs-Universität Freiburg, Killianstr. 5, 79106 Freiburg, Germany.
Get access Rights & Permissions [Opens in a new window]

Abstract

Multiple sclerosis is known to affect the myelin of the auditory pathway resulting in acute hearing loss. Two cases of sudden deafness due to multiple sclerosis have been evaluated by conventional audiometry, brainstem auditory evoked response audiometry and transtympanic electrocochleography. The abnormalities of the compound action potential in both patients (enhanced latency, abnormal adaptation using fast stimulus rate) and the normal receptor potentials (cochlear microphonic, summating potential), as well as the absence of brainstem responses suggest a disturbance of synchronization at the level of the first auditory neurone. The electrocochleography provides valuable information for the topodiagnosis of this and other neural hearing losses, especially in the absence of reliable brainstem responses.

Keywords

Multiple sclerosisHearing loss, sensorineuralAudiometry, evoked response
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 110 , Issue 3 , March 1996 , pp. 252 - 257
Copyright
Copyright © JLO (1984) Limited 1996

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Aran, J. M. (1973) Clinical measures of VHIth nerve function. Advances in Oto-Rhino-Laryngology 20: 374–394.CrossRefGoogle Scholar
Chiappa, K. H., Harrison, J. L., Brooks, E. B., Young, R. P. (1980) Brainstem auditory evoked responses in 200 patients with multiple sclerosis. Annals of Neurology 7: 135–143.CrossRefGoogle ScholarPubMed
Daugherty, W. T., Lederman, R. J., Nodar, R. H., Conomy, J. P. (1983) Hearing loss in multiple sclerosis. Archives of Neurology (Chicago) 40: 33–35.CrossRefGoogle ScholarPubMed
Dix, N. R. (1965) Observations upon the nerve fibre deafness of multiple sclerosis with particular reference to the phenomenon of loudness recruitment. Journal of Laryngology 79: 695–706.CrossRefGoogle Scholar
Fischer, C, Mauguiere, F., Ibanez, V., Confavreux, C, Chazot, G. (1985) The acute deafness of definite multiple sclerosis: BAEP patterns. Electroencephalography and Clinical Neurophysiology 61: 7–15.CrossRefGoogle ScholarPubMed
Franklin, D. J., Coker, N. J., Jenkins, H. A. (1989) Sudden sensorineural hearing loss as a presentation of multiple sclerosis. Archives of Otolaryngology, Head and Neck Surgery 115: 41–45.CrossRefGoogle ScholarPubMed
Gibson, W. P. R., Frasher, D. K., Kilkenny, G. P. G. (1983) Diagnostic significance of transtympanic electrocochleography in Meniere's disease. Annals of Otology, Rhinology and Laryngology 92: 155–159.CrossRefGoogle ScholarPubMed
Hopf, H. G, Eysheldt, M. (1978) Impaired refractory periods of peripheral sensory nerves in multiple sclerosis. Annals of Neurology 4: 499–501.CrossRefGoogle ScholarPubMed
Hopf, H. C, Maurer, K. (1983) Wave I of early auditory evoked potentials in multiple sclerosis. Electroencephalography and Clinical Neurophysiology 56: 31–37.CrossRefGoogle ScholarPubMed
Lehnhardt, E. (1975) Horstorungen bei Multipler Sklerose. HNO 23: 101–108.Google Scholar
Lang, E. (1967) Periphore neurologische Symptome bei multipler Sklerose. M. S. Thesis, University of Wurzburg.Google Scholar
McAlpine, D., Lumsden, C. E., Acheson, E. G. (1955) Multiple sclerosis. Livingstone, Edinburgh.Google ScholarPubMed
Miller, J. K., Cody, D. T. R., Griffing, T. (1969) Bekesy audiometry: demonstration of interrupted tone temporary threshold shift. Laryngoscope 79: 2135–2139.CrossRefGoogle ScholarPubMed
Noffsinger, D., Olser, W. O., Carhart, R., Hart, C. W., Sahgal, V. (1972) Auditory and vestibular aberrations in multiple sclerosis. Acta Otolaryngologica (Stockholm) (Suppl) 303: 3–61.Google ScholarPubMed
Pollock, M., Calder, C, Allpress, S. (1977) Peripheral nerve abnormality in multiple sclerosis. Annals of Neurology 2: 41–48.CrossRefGoogle ScholarPubMed