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Hearing disability before and after radiotherapy for nasopharyngeal carcinoma

Published online by Cambridge University Press:  29 June 2007

W. K. Low  and
K. W. Fong
W. K. Low*
Affiliation:
Department of Otolaryngology, Singapore General Hospital, Singapore 0316, Republic of Singapore.
K. W. Fong
Affiliation:
Therapeutic Radiology, Singapore General Hospital, Singapore 0316, Republic of Singapore.
*
Address for correspondence: Dr W. K. Low, Department of Otolaryngology, Singapore General Hospital, Singapore 0316, Republic of Singapore. Fax: 65-2262079
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Abstract

This paper evaluates post-irradiation hearing changes in patients with nasopharyngeal carcinoma (NPC) from a disability orientated approach, which takes into account binaural hearing. Newly diagnosed patients with NPC were studied before radiotherapy, and at four to 12 months (mean 9.2 months) after radiotherapy, provided they remained disease-free. Each patient was examined clinically and with pure tone audiograms. Tympanometry was used to confirm middle ear effusion. Averaged hearing thresholds over 0.5,1 and 2 kHz were evaluated. If abnormal (>30 dB), the resultant hearing disability was illustrated by a modified Glasgow Plot. Twenty-three males and 10 females completed the study. Middle ear effusions resulted in 39.3 per cent (binaural in two patients) and 33.3 per cent (binaural in five patients) of patients having hearing disability pre- and post-irradiation respectively. No patient had hearing disability as a result of a sensorineural loss. It is recommended that future reporting of post-irradiation hearing changes in patients with NPC, as in middle ear surgery, be considered from a disability-orientated approach.

Keywords

Otitis media with effusionNasopharyngeal neoplasmsRadiotherapyDeafness
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 110 , Issue 2 , February 1996 , pp. 121 - 123
Copyright
Copyright © JLO (1984) Limited 1996

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References

Borsanyi, S., Blanchard, C. L., Thorn, B. (1961) The effects of ionising radiation on the ear. Annals of Otology, Rhinology and Laryngology 70: 255–262.CrossRefGoogle Scholar
Browning, G. G., Gatehouse, S., Swan, I. R. C. (1991) The Glasgow benefit plot: a new method for reporting benefits from middle ear surgery. Laryngoscope 101: 180–185.CrossRefGoogle ScholarPubMed
Lau, S. K., Wei, W. I., Sham, J., Hui, Y., Choy, D. (1992) Effects of irradiation on middle ear effusion due to nasopharyngeal carcinoma. Clinical Otolaryngology 17: 246–250.CrossRefGoogle ScholarPubMed
Morretti, J. A. (1976) Sensorineural hearing loss following radiotherapy to the nasopharynx. Laryngoscope 86: 598–602.CrossRefGoogle Scholar
Skinner, D. W., van Hasselt, C. A. (1991) A study of the complications of grommet insertion for secretory otitis media in the presence of nasopharyngeal carcinoma. Clinical Otolaryngology 16: 480–482.CrossRefGoogle ScholarPubMed
Symth, G. D. L., Patterson, C. C. (1985) Results of middle ear reconstruction: do patients and surgeons agree? American Journal of Otology 6: 276–279.Google Scholar
Tami, Y. P., Finkelstein, Y., Zohar, Y. (1989) Post irradiation hearing loss. Audiology 28: 121–126.Google Scholar
Tang, N. L. S., Choy, A. T. K., John, D. G., van Hasselt, C. A. (1992) The otological status of patients with nasopharyngeal carcinoma after megavoltage radiotherapy. Journal of Laryngology and Otology 106: 1055–1058.CrossRefGoogle ScholarPubMed
Toner, J. G., Smyth, G. D. L. (1993) Comparison of methods of evaluating hearing benefit of middle ear surgery. Journal of Laryngology and Otology 107: 4–5.CrossRefGoogle ScholarPubMed
Winther, F. O. (1970) X-ray irradiation of the inner ear of the guinea pig–an electron microscopic study of the degenerating hair cells of the Organ of Corti. Acta Otolaryngologica (Stockholm) 69: 61–76.CrossRefGoogle Scholar