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Giant basal cell carcinoma of the face: surgical management and challenges for reconstruction

Published online by Cambridge University Press:  17 December 2015

A Maimaiti ,
A Mijiti ,
A Yarbag  and
A Moming
A Maimaiti
Affiliation:
Department of Oral and Maxillofacial Surgery, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People's Republic of China Stomatological Research Institute of Xinjiang Uyghur Autonomous Region, Urumqi, Xinjiang, People's Republic of China
A Mijiti
Affiliation:
Department of Oral and Maxillofacial Surgery, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People's Republic of China Stomatological Research Institute of Xinjiang Uyghur Autonomous Region, Urumqi, Xinjiang, People's Republic of China
A Yarbag
Affiliation:
Marmara Eye Center, Sakarya, Turkey
A Moming*
Affiliation:
Department of Oral and Maxillofacial Surgery, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People's Republic of China Stomatological Research Institute of Xinjiang Uyghur Autonomous Region, Urumqi, Xinjiang, People's Republic of China
*
Address for correspondence: Dr Adili Moming, Department of Oral and Maxillofacial Surgery, First Affiliated Hospital Xinjiang Medical University, No. 137 South Li Yu-Shan Road, New City District, 830054 Urumqi, Xinjiang Uyghur Autonomous Region, PR China E-mail: [email protected]
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Abstract

Background:

Giant basal cell carcinoma, in which the tumour measures 5 cm or greater in diameter, is a very rare skin malignancy that accounts for less than 1 per cent of all basal cell tumours. Very few studies have reported on the incidence, resection and reconstruction of this lesion worldwide.

Methods:

In total, 17 patients with giant basal cell carcinoma of the head and neck region underwent surgical excision and reconstruction at our hospital. Medical charts were retrospectively reviewed and analysed.

Results:

The lesion was usually in the forehead, eyelid, lips or nasal-cheek region. The greatest diameter ranged from 5 to 11 cm, with 5–6 cm being the most common size at the time of presentation. All patients had their tumour resected and reconstructed in a single-stage procedure, mostly with a local advancement flap, and with no post-operative flap failure.

Conclusion:

Giant basal cell carcinoma of the head and neck can be successfully treated with a local flap in a single-stage approach.

Keywords

Basal Cell CarcinomaFacial NeoplasmsDermatologic SurgeryReconstructive Surgical Procedures
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 130 , Issue 2 , February 2016 , pp. 176 - 182
Copyright
Copyright © JLO (1984) Limited 2015 

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References

1Koplin, L, Zarem, HA. Recurrent basal cell carcinoma. A review concerning the incidence, behavior, and management of recurrent basal cell carcinoma, with emphasis on the incompletely excised lesion. Plast Reconstr Surg 1980;65:656–64CrossRefGoogle ScholarPubMed
2Fattah, A, Pollock, J, Maheshwar, A, Britto, JA. Big bad BCCs: craniofacial resection and reconstruction for atypical basal cell carcinomata. J Plast Reconstr Aesthet Surg 2010;63:e433–41CrossRefGoogle ScholarPubMed
3Manstein, CH, Manstein, ME, Beidas, OE. Giant basal cell carcinoma: 11-year follow-up and seven new cases. Plast Reconstr Surg 2011;128:1105–6CrossRefGoogle ScholarPubMed
4Veronese, F, Farinelli, P, Zavattaro, E, Zuccoli, R, Bonvini, D, Leigheb, G et al. Basal cell carcinoma of the head region: therapeutical results of 350 lesions treated with Mohs micrographic surgery. J Eur Acad Dermatol Venereol 2012;26:838–43CrossRefGoogle ScholarPubMed
5Ding, C, Lin, MS. Treatment of basal cell carcinoma: a review [in Chinese]. Oncol Prog 2011;9:77–84Google Scholar
6Page, DL, Fleming, ID, Fritz, A. AJCC Cancer Staging Manual, 6th edn.New York: Springer-Verlag, 2002Google Scholar
7Snow, SN, Sahl, W, Lo, JS, Mohs, FE, Warner, T, Dekkinga, JA et al. Metastatic basal cell carcinoma. Report of five cases. Cancer 1994;73:328–353.0.CO;2-U>CrossRefGoogle ScholarPubMed
8Sahl, WJ, Snow, SN, Levine, NS. Giant basal cell carcinoma: report of two cases and review of the literature. J Am Acad Dermatol 1994;30:856–9CrossRefGoogle ScholarPubMed
9Kiiski, V, de Vries, E, Flohil, SC, Bijl, MJ, Hofman, A, Stricker, BH et al. Risk factors for single and multiple basal cell carcinomas. Arch Dermatol 2010;146:848–55CrossRefGoogle ScholarPubMed
10Zoccali, G, Pajand, R, Papa, P, Orsini, G, Lomartire, N, Giuliani, M. Giant basal cell carcinoma of the skin: literature review and personal experience. J Eur Acad Dermatol Venereol 2012;26:942–52CrossRefGoogle ScholarPubMed
11Eckhoff, NL. Recurrent, multiple, and metastasizing basal-celled carcinomata. Br J Plast Surg 1951;3:264–81CrossRefGoogle ScholarPubMed
12Archontaki, M, Stavrianos, SD, Korkolis, DP, Arnogiannaki, N, Vassiliadis, V, Liapakis, IE. Giant basal cell carcinoma: clinicopathological analysis of 51 cases and review of the literature. Anticancer Res 2009;29:2655–63Google ScholarPubMed
13Randle, HW, Roenigk, RK, Brodland, DG. Giant basal cell carcinoma (T3): who is at risk? Cancer 1993;72:1624–303.0.CO;2-D>CrossRefGoogle ScholarPubMed
14Roenigk, RK, Ratz, JL, Bailin, PL, Wheeland, RG. Trends in the presentation and treatment of basal cell carcinomas. J Dermatol Surg Oncol 1986;12:860–5CrossRefGoogle ScholarPubMed
15LeBoit, PE, Burg, G, Weedon, D, Sarasin, A, eds. World Health Organization Classification of Tumors. Pathology and Genetics of Skin Tumors. Lyon: IARC Press, 2006;10–33Google Scholar
16Martin, RC 2nd, Edwards, MJ, Cawte, TG, Sewell, CL, McMasters, KM. Basosquamous carcinoma: analysis of prognostic factors influencing recurrence. Cancer 2000;88:1365–93.0.CO;2-Y>CrossRefGoogle ScholarPubMed
17Talmi, YP, Gal, R, Finkelstein, Y, Nobel, M, Shvilli, I, Zohar, Y. Squamous and basal cell cancers directly invading major salivary glands. Ann Plast Surg 1991;26:483–7CrossRefGoogle ScholarPubMed
18Ting, PT, Kasper, R, Arlette, JP. Metastatic basal cell carcinoma: report of two cases and literature review. J Cutan Med Surg 2005;9:10–15CrossRefGoogle ScholarPubMed
19Dubin, N, Kopf, AW. Multivariate risk score for recurrence of cutaneous basal cell carcinomas. Arch Dermatol 1983;119:373–7CrossRefGoogle ScholarPubMed
20Manstein, CH, Gottlieb, N, Manstein, ME, Manstein, G. Giant basal cell carcinoma: a series of seven T3 tumors without metastasis. Plast Reconstr Surg 2000;106:653–6CrossRefGoogle ScholarPubMed
21McCombe, D, Donato, R, Hofer, SO, Morrison, W. Free flaps in the treatment of locally advanced malignancy of the scalp and forehead. Ann Plast Surg 2002;48:600–6CrossRefGoogle ScholarPubMed