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Fibrous dysplasia of the nasal bone: case reports and literature review

Published online by Cambridge University Press:  30 October 2013

G Wong*
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Charing Cross Hospital, London, UK
P Randhawa
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Charing Cross Hospital, London, UK
J Stephens
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Charing Cross Hospital, London, UK
H Saleh
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Charing Cross Hospital, London, UK
*
Address for correspondence: Mr G Wong, Department of Otolaryngology, Royal Free Hospital, Pond Street, London, NW3 2QG, UK E-mail: [email protected]

Abstract

Introduction:

Craniofacial fibrous dysplasia commonly affects the larger mandible and the maxillary bones. Although involvement of the frontal, temporal and sphenoid bones has been described, fibrous dysplasia of the nasal bone has not been previously described; the two cases reported here have been made rarer by their isolated involvement. Clinical management is dependent on disease activity and patient symptoms.

Objective:

To present two cases of isolated fibrous dysplasia of the nasal bone: a 46-year-old woman with gradual widening of the nasal bridge and a 47-year-old man with an incidental finding of a nasal bone mass.

Method:

Two case reports.

Results:

The 46-year-old woman underwent excision of the lesion while the 47-year-old man opted for watchful waiting.

Conclusion:

We have presented the first case reports of fibrous dysplasia of the nasal bone. The care of these patients should be customised to their needs and wishes.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 2013 

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References

1Feller, L, Wood, NH, Khammissa, RA, Lemmer, J, Raubenheimer, EJ. The nature of fibrous dysplasia. Head Face Med 2009;5:22CrossRefGoogle ScholarPubMed
2Dumitrescu, CE, Collins, MT. McCune-Albright, syndrome. Orphanet J Rare Dis 2008;3:12CrossRefGoogle Scholar
3Gupta, N, Gupta, R, Bakshi, J, Rajwanshi, A. Fine needle aspiration cytology in a case of fibrous dysplasia of jaw. Diagn Cytopathol 2009;37:920–2CrossRefGoogle Scholar
4Okada, H, Matsumoto, T, Oomine, H, Kaneda, T, Yamamoto, H. Rare example of the use of fine-needle aspiration cytology for periapical osseous dysplasia. Diagn Cytopathol 2011;39:510–3CrossRefGoogle ScholarPubMed
5Riminucci, M, Robey, PG, Saggio, I, Bianco, P. Skeletal progenitors and the GNAS gene: fibrous dysplasia of bone read through stem cells. J Mol Endocrinol 2010;45:355–64CrossRefGoogle ScholarPubMed
6Charpurlat, RD, Meunier, PJ. Fibrous dysplasia of bone. Baillieres Best Pract Res Clin Rheumatol 2000;14:385–98CrossRefGoogle Scholar
7Slootweg, PJ, Müller, H. Differential diagnosis of fibro-osseous jaw lesions. A histological investigation on 30 cases. J Craniomaxillofac Surg 1990;18:210–14CrossRefGoogle ScholarPubMed
8Yochum, TR, Rowe, LJ. Tumors and tumor-like processes. In: Yochum, TR, Rowe, LJ, eds. Essentials of Skeletal Radiology, 3rd edn.Philadelphia: Lippincott Williams & Wilkins, 2005;1334Google Scholar
9Cai, M, Ma, L, Xu, G, Gruen, P, Li, J, Yang, M et al. Clinical and radiological observation in a surgical series of 36 cases of fibrous dysplasia of the skull. Clin Neurol Neurosurg 2012;114:254–9CrossRefGoogle Scholar
10Amit, M, Collins, MT, FitzGibbon, EJ, Butman, JA, Fliss, DM, Gil, Z. Surgery versus watchful waiting in patients with craniofacial fibrous dysplasia – a meta-analysis. PLoS One 2011;6:e25179CrossRefGoogle ScholarPubMed
11Michael, CB, Lee, AG, Patrinely, JR, Stal, S, Blacklock, JB. Visual loss associated with fibrous dysplasia of the anterior skull base. Case report and review of the literature. J Neurosurg 2000;92:350–4CrossRefGoogle ScholarPubMed
12Posnick, JC. Fibrous dysplasia of the craniomaxillofacial region: current clinical perspectives. Br J Oral Maxillofac Surg 1998;36:264–73CrossRefGoogle ScholarPubMed
13Ooi, EH, Glicksman, JT, Vescan, AD, Witterick, IJ. An alternative management approach to paranasal sinus fibro-osseous lesions. Int Forum Allergy Rhinol 2011;1:5563CrossRefGoogle ScholarPubMed
14Chapurlat, RD. Medical therapy in adults with fibrous dysplasia of bone. J Bone Miner Res 2006;21(suppl 2):114–9CrossRefGoogle ScholarPubMed
15Lane, JM, Khan, SN, O'Connor, WJ, Nydick, M, Hommen, JP, Schneider, R et al. Bisphosphonate therapy in fibrous dysplasia. Clin Orthop Relat Res 2001;382:612CrossRefGoogle Scholar
16Kitagawa, Y, Tamai, K, Ito, H. Oral alendronate treatment for polyostotic fibrous dysplasia: a case report. J Orthop Sci 2004;9:521–5CrossRefGoogle ScholarPubMed