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Fatal massive upper respiratory tract haemorrhage: an unusual complication of localized amyloidosis of the larynx

Published online by Cambridge University Press:  29 June 2007

Louis Tsun-Cheung Chow ,
Wing-Hing Chow  and
Bobby Shui-fung Shum
Louis Tsun-Cheung Chow*
Affiliation:
Institute of Pathology, Queen Elizabeth Hospital, Hong Kong
Wing-Hing Chow
Affiliation:
Department of Medicine, Grantham HospitalAberdeen, Hong Kong
Bobby Shui-fung Shum
Affiliation:
Forensic Pathology Service, Department of Health, Hong Kong.
*
Dr Louis T. C. Chow, Institute of Pathology, Queen Elizabeth Hospital, Wylie Road, Kowloon, Hong Kong. Fax: (852)-385-2455
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Abstract

Localized amyloidosis of the larynx is usually described as a non-bleeding lesion. We report a patient with localized laryngeal amyloidosis who developed a massive upper respiratory tract haemorrhage and died. This potentially fatal complication of localized amyloidosis of the larynx merits recognition as the disease could be controlled in most instances by surgical excision of the amyloid deposit.

Keywords

AmyloidosisLarynxHaemorrhageUpper respiratory tract
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 107 , Issue 1 , January 1993 , pp. 51 - 53
Copyright
Copyright © JLO (1984) Limited 1993

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References

Bjornsson, S., Johannsson, J. H., Sigurjonsson, F. (1987) Localized primary amyloidosis of the stomach presenting with gastric haemorrhage. Acta Medica Scandinavica, 221: 115–119.CrossRefGoogle Scholar
Brownstein, M. H., Helwig, E. B. (1970) The cutaneous amyloidosis. I. Localized forms. Archives of Dermatology, 102: 8–19.CrossRefGoogle ScholarPubMed
Cosgrove, G. R., Leblanc, R., Meagher-Villemure, K., Ethier, R. (1985) Cerebral amyloid angiopathy. Neurology, 35: 625–631.CrossRefGoogle ScholarPubMed
Fujihara, S., Glenner, G. G. (1981) Primary localized amyloidosis of the genitourinary tract. Immunohistochemical study on 11 cases. Laboratory Investigation, 44: 55–60.Google Scholar
Gilles, C., Brucher, J. M., Khoubesserian, P., Vanderhaeghen, J. J. (1984) Cerebral amyloid angiopathy as a cause of multiple intracerebral hemorrhages. Neurology, 34: 730–735.CrossRefGoogle ScholarPubMed
Macmanus, Q., Okies, J. E. (1976) Amyloidosis of the stomach: report of an unusual case and review of the literature. American Surgeon, 42: 607–610.Google ScholarPubMed
Mandybur, T. I. (1986) Cerebral amyloid angiopathy: The vascular pathology and complications. Journal of Neuropathology and Experimental Neurology, 45: 79–90.CrossRefGoogle ScholarPubMed
McAlpine, J. C.Fuller, A. P. (1964) Localized laryngeal amyloidosis. A report of a case with a review of the literature. Journal of Laryngology and Otology, 78: 296–314.CrossRefGoogle ScholarPubMed
Michaels, L., Hyams, V. J. (1979) Amyloid in localized deposits and plasmacytomas of the respiratory tract. Journal of Pathology 128: 29–38.CrossRefGoogle ScholarPubMed
New, G. B. (1919) Amyloid tumours of the upper air passages. Laryngoscope, 29: 327–341.CrossRefGoogle Scholar
Shaheen, N. A., Salman, S. D., Nassar, V. H. (1975) Fatal bronchopulmonary hemorrhage due to unrecognized amyloidosis. Archives of Otolaryngology, 101: 259–261.CrossRefGoogle ScholarPubMed
Simpson, G. T. II, Skinner, M., Strong, M. S., Cohen, A. S. (1984) Localized amyloidosis of the head and neck and upper aerodigestive and lower respiratory tracts. Annals of Otology, Rhinology and Laryngology, 93: 374–379.CrossRefGoogle ScholarPubMed
Stark, D. B., New, G. B. (1949) Amyloid tumors of larynx, trachea or bronchi; report of 15 cases. Annals of Otology, Rhinology and Laryngology, 58: 117–134.CrossRefGoogle ScholarPubMed
Van Fijswijk, M. H., Van Heusden, C. W. (1979) The potassium permanganate method: A reliable method for differentiating amyloid AA from other forms of amyloid in routine laboratory practice. American Journal of Pathology, 97: 43–58.Google Scholar
Westermark, P., Sletten, K., Pitkanen, P., Natvig, J. B., Lindholm, C. E. (1982) Localized laryngeal amyloidosis: partial characterization of an amyloid fibril protein AL. Molecular Immunology, 19: 447–450.CrossRefGoogle ScholarPubMed
Wright, J. R., Calkins, E., Humphrey, R. L. (1977) Potassium permanganate reaction in amyloidosis: A histologic method to assist in differentiating forms of this disease. Laboratory Investigation 36: 274–281.Google ScholarPubMed
Yood, R. A., Skinner, M., Rubinow, A., Talarico, L., Cohen, A. S. (1983) Bleeding manifestations in 100 patients with amyloidosis. Journal of the American Medical Association, 249: 1322–1324.CrossRefGoogle ScholarPubMed