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Ewing's sarcoma of the masseter muscle

Published online by Cambridge University Press:  31 May 2011

H A Osborn
Affiliation:
Schulich School of Medicine, University of Western Ontario, London, Canada
B Wehrli
Affiliation:
Department of Pathology, London Health Sciences Centre, Ontario, Canada
J H Franklin
Affiliation:
Department of Otolaryngology, London Health Sciences Centre, Ontario, Canada
K Fung*
Affiliation:
Department of Otolaryngology, London Health Sciences Centre, Ontario, Canada
*
Address for correspondence: Dr. Kevin Fung, Department of Otolaryngology – Head and Neck Surgery, London Health Sciences Centre – Victoria Hospital, 800 Commissioners Road East London, Ontario, CanadaN6A 5W9 E-mail: [email protected]

Abstract

Objective:

To present a case of extraskeletal Ewing's sarcoma originating in the masseter muscle, and to review the diagnosis and management of these rare tumours.

Methods:

Case report and literature review.

Results:

We report a patient with Ewing's sarcoma of the masseter muscle with mandibular invasion. She was treated with induction chemotherapy, salvage surgery and free flap reconstruction.

Conclusion:

This case highlights the management of these rare tumours. Aggressive multi-modal treatment, including multi-agent chemotherapy, surgical resection and irradiation, appears to offer the best prognosis. Contemporary reconstructive techniques can restore function and form in cases with challenging defects.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 2011

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References

1Cotterill, SJ, Ahrens, S, Paulussen, M, Jurgens, HF, Voute, PA, Gadner, H et al. Prognostic factors in Ewing's tumor of bone: analysis of 975 patients from the European Intergroup Cooperative Ewing's Sarcoma Study Group. J Clin Oncol 2000;18:3108–14Google Scholar
2Allam, A, El-Husseiny, G, Khafaqa, Y, Kandil, A, Gray, A, Ezzat, A et al. Ewing's sarcoma of the head and neck: a retrospective analysis of 24 cases. Sarcoma 1999;3:1115CrossRefGoogle ScholarPubMed
3Siegal, GP, Oliver, WR, Reinus, WR, Gilula, LA, Foulkes, MA, Kissane, JM et al. Primary Ewing's sarcoma involving the bones of the head and neck. Cancer 1987;60:2829–403.0.CO;2-S>CrossRefGoogle ScholarPubMed
4Ali, S, MacKenzie, K, Reid, R, O'Neill, G, Ganly, I. Cervical extraskeletal Ewing's sarcoma: case report demonstrating radiological features and management. J Laryngol Otol 2008;122:9981001Google Scholar
5Kinsella, TJ, Triche, TJ, Dickman, PS, Costa, J, Tepper, JE, Glaubiger, D. Extraskeletal Ewing' s sarcoma: results of combined modality treatment. J Clin Oncol 1983;1:489–95CrossRefGoogle ScholarPubMed
6Cho, SI, Park, YH, Cho, JH, Ryoo, BY, Yang, SH, Youn, SM et al. Extraskeletal Ewing's sarcoma of the head and neck presenting as blindness. Korean J Intern Med 2007;22:133–7Google Scholar
7Chao, TK, Chang, YL, Sheen, TS. Extraskeletal Ewing's sarcoma of the scalp. J Laryngol Otol 2000;114:73–5Google Scholar
8Yang, YS, Hong, KH. Extraskeletal Ewing's sarcoma of the larynx. J Laryngol Otol 2004;118:62–4CrossRefGoogle ScholarPubMed
9Weinreb, I, Goldstein, D, Perez-Ordonez, B. Primary extraskeletal Ewing family tumor with complex epithelial differentiation: a unique case arising in the lateral neck presenting with Horner syndrome. Am J Surg Pathol 2008;32:1742–8Google Scholar
10Mills, SE. Neuroectodermal neoplasms of the head and neck with emphasis on neuroectodermal carcinomas. Mod Pathol 2002;15:264–78CrossRefGoogle ScholarPubMed
11Ewing, J. Diffuse endothelioma of bone. Proc N Y Pathol Soc 1921;21:1724Google Scholar
12Tefft, M, Vawter, GF, Mitus, A. Paravertebral “round cell” tumors in children. Radiology 1969;92:1501–9CrossRefGoogle ScholarPubMed
13O'Keefe, F, Lorigan, JG, Wallace, S. Radiological features of extraskeletal Ewing sarcoma. Br J Radiol 1990;63:456–60CrossRefGoogle Scholar
14Heare, T, Hensley, M, Dell'Orfano, S. Bone tumors: osteosarcoma and Ewing's sarcoma. Curr Opin Pediatr 2009;21:365–72CrossRefGoogle ScholarPubMed
15Zagar, TM, Triche, TJ, Kinsella, T. Extraosseous Ewing's sarcoma: 25 years later. J Clin Oncol 2008;26:4230–2CrossRefGoogle ScholarPubMed
16Venkitaraman, R, George, M, Ramanan, SG, Sagar, TG. A single institution experience of combined modality management of extra skeletal Ewings sarcoma. World J Surg Onc 2007;5:3CrossRefGoogle ScholarPubMed
17Bacci, G, Longhi, A, Ferrari, S, Mercuri, M, Barbieri, E, Bertoni, F et al. Pattern of relapse in 290 patients with non-metastatic Ewing's sarcoma family tumors treated at a single institution with adjuvant and neoadjuvant chemotherapy between 1972 and 1999. Eur J Surg Onc 2006;32:974–9Google Scholar
18Verrill, MW, Judson, IR, Harmer, CL, Fisher, C, Thomas, JM, Wiltshaw, E. Ewing's sarcoma and primitive neuroectodermal tumor in adults: are they different from Ewing's sarcoma and primitive neuroectodermal tumor in children? J Clin Oncol 1997;15:2611–21Google Scholar
19Paulino, AC, Nguyen, TX, Mai, WY. An analysis of primary site control and late effects according to local control modality in non-metastatic Ewing sarcoma. Pediatr Blood Cancer 2007;48:423–9CrossRefGoogle ScholarPubMed