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Epidemiological study of cholesteatoma in Fukuoka City

Published online by Cambridge University Press:  23 February 2015

S Shibata ,
K Murakami ,
Y Umeno  and
S Komune
S Shibata*
Affiliation:
Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
K Murakami
Affiliation:
Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Y Umeno
Affiliation:
Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
S Komune
Affiliation:
Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
*
Address for correspondence: Shumei Shibata, Department of Otorhinolaryngology – Head and Neck Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan Fax:+81 92 6425685 E-mail: [email protected]
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Abstract

Objective and design:

To investigate the pathogenesis of cholesteatoma, we planned to conduct a cohort study. As a first step, we conducted an epidemiological study in Fukuoka City, Japan to determine the incidence of cholesteatoma treated both with and without surgery. We also conducted a case–control study to investigate the pathogenesis of cholesteatoma.

Results:

The annual incidence of cholesteatoma, including cases treated without surgery, was 6.8–10.0 in a population of 100 000. The results of the case–control study suggested that a past history of otitis media and habitual sniffing caused by a patulous eustachian tube play a role in the pathogenesis of cholesteatoma.

Conclusions:

The annual incidence of cholesteatoma, including cases treated without surgery, was considered to not be high enough to perform a cohort study. The results of the case–control study suggest that otitis media and habitual sniffing due to a patulous eustachian tube, contribute to the onset of cholesteatoma.

Keywords

Cholesteatoma, Middle EarEpidemiologic StudiesEziology; Otitis Media with Effusion
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 129 , Issue S2 , March 2015 , pp. S6 - S11
Copyright
Copyright © JLO (1984) Limited 2015 

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References

1Bezold, F. Perforation of Shrapnells membrane and occlusion of the tubes an aetiological study. Archives of Otolaryngology 1890;19:232–54Google Scholar
2Tos, M. Incidence, etiology and pathogenesis of cholesteatoma in children. Adv Otorhinolaryngol 1988;40:110–17Google ScholarPubMed
3Sudhoff, H and Tos, M. Pathogenesis of attic cholesteatoma: clinical and immunohistochemical support for combination of retraction theory and proliferation theory. Am J Otolaryngol 2000;21:786–92Google ScholarPubMed
4Jordan, RE. Secretory otitis media in etiology of cholesteatoma. Arch Otolaryngol 1963;78:261–5Google Scholar
5Tos, M, Poulsen, G. Attic retractions following secretory otitis. Acta Otolaryngol 1980;89:479–86CrossRefGoogle ScholarPubMed
6Magnuson, B. Tubal closing failure in retraction type cholesteatoma and adhesive middle ear lesions. Acta Otolaryngol 1978;86:408–17CrossRefGoogle ScholarPubMed
7Fujishima, M, Kiyohara, Y, Kato, I, Ohmura, T, Iwamoto, H, Nakashima, K et al. Diabetes and cardiovascular disease in a prospective population survey in Japan: The Hisayama Study. Diabetes 1996;45(suppl 3):14–16Google Scholar
8Kiyohara, Y, Ueda, K, Hasuo, Y, Wada, J, Kawano, H, Kato, I et al. Incidence and prognosis of subarachnoid hemorrhage in a Japanese rural community. Stroke 1989;20:1150–5CrossRefGoogle Scholar
9Takahashi, Y, Kobayashi, T, Takasaka, T. Epidemiological study on cholesteatoma in Japan [in Japanese]. Otology Japan 1998;8:165–70Google Scholar
10Homoe, P, Bretlau, P. Cholesteatoma in Greenlanddic Inuitt: a retrospective analysis of known cases. In: Nakano, Y ed. Cholesteatoma and Mastoid Surgery. Amsterdam: Kugler, 1993;241–4.Google Scholar
11Harker, LA. Cholesteatoma an incidence study. In: McCabe, BF, Sade, J, Abramson, M ed. Proceedings of Cholesteatoma. First Int Conf. Aesculapiusct, Birmingham, AL. 1977, 308–9.Google Scholar
12Kemppainen, H, Puhakka, H, Laippala, P, Sipila, M, Manninen, M, Karma, P. Epidemiology and aetiology of middle ear cholesteatoma. Acta Otolaryngol 1999;119:568–72Google Scholar
13Duffy, LC, Faden, H, Wasielewski, R, Wolf, J, Krystofik, D. Exclusive breastfeeding protects against bacterial colonization and day care exposure to otitis media. Pediatrics 1997;100:E7CrossRefGoogle ScholarPubMed
14Casselbrant, ML, Mandel, EM, Fall, PA, Rockette, HE, Kurs-Lasty, N, Bluestone, CD. et al. The heritability of otitis media: a twin and triplet study. J Am Med Assoc 1999;282:2125–30CrossRefGoogle ScholarPubMed
15Kobayashi, T, Yaginuma, Y, Takahashi, Y, Takasaka, T. Incidence of sniff-related cholesteatoma. Acta Otolaryngol 1996;116:74–6Google Scholar
16Ohta, S, Sakagami, M, Suzuki, M, Mishiro, Y. Eustachian tube function and habitual sniffing in middle ear cholesteatoma. Otol Neurotol 2009;30:48–53Google Scholar