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The efficacy and safety of radiofrequency ablation for allergic rhinitis: a systematic review and meta-analysis

Published online by Cambridge University Press:  04 December 2024

Xi Zhang Open the ORCID record for Xi Zhang [Opens in a new window] ,
Min Yan ,
Qicheng Deng  and
Ling Yang
Xi Zhang
Affiliation:
Department of Otolaryngology Head and Neck Surgery of Nanchong Central Hospital, Nanchong, China
Min Yan
Affiliation:
Nanchong Central Hospital, Nanchong, China
Qicheng Deng
Affiliation:
Public Health Clinical Center of Chengdu, Chengdu, China
Ling Yang*
Affiliation:
Department of Otolaryngology Head and Neck Surgery of Dazhou Central Hospital, Dazhou, China
*
Corresponding author: Ling Yang; Email: [email protected]
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Abstract

Objective

This systematic review aims to synthesise findings from randomised, controlled trials and assess the efficacy and safety of radiofrequency ablation in treating allergic rhinitis.

Methods

A thorough search was conducted across PubMed, the Cochrane Library, Embase, Web of Science, China National Knowledge Infrastructure, WanFang, Chinese Scientific Journal, and Chinese Biomedical Literature databases from their inception until October 2023. The primary outcome measure was the total effective rate, with secondary outcomes including adverse events.

Results

This review included 15 randomised, controlled trials involving 1430 patients. The pooled analysis revealed a statistically significant effect on the total effective rate (odds ratio = 3.27, 95 per cent confidence interval = 2.37 to ~4.51). However, no statistical significance was observed in adverse events (odds ratio = 1.18, 95 per cent confidence interval = 0.67 to ~2.08).

Conclusions

Based on the analytical results, radiofrequency ablation emerges as an efficacious and safe treatment modality for allergic rhinitis. Given the constraints posed by a limited sample size, it is imperative that forthcoming clinical trials adhere rigorously to the gold standard of randomised, controlled trials for the purpose of corroborating these conclusions.

Keywords

radiofrequency ablationallergic rhinitissystematic reviewmeta-analysis
Type
Review Article
Information
The Journal of Laryngology & Otology , Volume 138 , Issue 12 , December 2024 , pp. 1120 - 1129
Copyright
Copyright © The Author(s), 2024. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED

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Footnotes

Ling Yang takes responsibility for the integrity of the content of the paper

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