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Effects of thiocolchicoside, a commonly used myorelaxant, on the acoustic reflex

Published online by Cambridge University Press:  02 March 2017

H H Arslan ,
S Cebeci ,
U Yildizoglu ,
S Pusat  and
F Yavuz
H H Arslan
Affiliation:
Department of Otorhinolaryngology Head and Neck Surgery, Gulhane Military Medical Academy, Etlik, Ankara, Turkey
S Cebeci*
Affiliation:
Department of Otorhinolaryngology Head and Neck Surgery, Zübeyde Hanım Maternity Hospital, Etlik, Ankara, Turkey
U Yildizoglu
Affiliation:
Department of Otorhinolaryngology Head and Neck Surgery, Beytepe Military Hospital, Cankaya, Ankara, Turkey
S Pusat
Affiliation:
Department of Neurosurgery, Etimesgut Military Hospital, Yenimahalle, Ankara, Turkey
F Yavuz
Affiliation:
Department of Physical Therapy and Rehabilitation, Etimesgut Military Hospital, Yenimahalle, Ankara, Turkey
*
Address for correspondence: Dr Suleyman Cebeci, Serhat Mahallesi, 1292 Sokak, No: 5/B/30 Yenimahalle, Ankara 06374, Turkey Fax: 00 90 312 323 8191 E-mail: [email protected]
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Abstract

Objective:

To determine whether thiocolchicoside, a commonly used myorelaxant, may impair the acoustic reflex.

Methods:

Forty-two patients scheduled to receive thiocolchicoside treatment for different reasons were enrolled in the study. Acoustic reflex thresholds at 500, 1000, 2000 and 4000 Hz were determined and analysed statistically pre-treatment and on the 5th day of treatment.

Results:

Increases were observed in the mean acoustic reflex thresholds on the 5th day of treatment compared to pre-treatment, at all frequencies, except right contralateral thresholds at 500 and 2000 Hz. These increases were statistically significant for right ipsilateral thresholds at 2000 and 4000 Hz, left ipsilateral thresholds at 500, 1000, 2000 and 4000 Hz, and left contralateral thresholds at 2000 and 4000 Hz (p ≤ 0.05), but not at other frequencies (p > 0.05).

Conclusion:

Muscle relaxant drugs, especially those affecting the central nervous system, may weaken the stapedial muscle so that the ability of noise to cause acoustic trauma may become evident. For this reason, physicians should advise their patients to avoid loud noises when muscle relaxant therapy is prescribed.

Keywords

ReflexAcousticAcoustic TraumaCentrally Acting Muscle Relaxants
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 131 , Issue 6 , June 2017 , pp. 497 - 500
Copyright
Copyright © JLO (1984) Limited 2017 

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Footnotes

Presented as a poster at the 11th International Congress of Otorhinolaryngology and Head and Neck Surgery, 17–19 April 2014, Ankara, Turkey.

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