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Effect of Beconase nasal spray on olfactory function in post-nasal polypectomy patients: a prospective controlled trial

Published online by Cambridge University Press:  29 June 2007

Mohammed El Naggar ,
Savita Kale ,
Chris Aldren  and
Frank Martin
Mohammed El Naggar
Affiliation:
Department of Otolaryngology, North Riding Infirmary, Middlesbrough, Cleveland, UK.
Savita Kale
Affiliation:
Department of Otolaryngology, North Riding Infirmary, Middlesbrough, Cleveland, UK.
Chris Aldren*
Affiliation:
Department of Otolaryngology, North Riding Infirmary, Middlesbrough, Cleveland, UK.
Frank Martin
Affiliation:
Department of Otolaryngology, North Riding Infirmary, Middlesbrough, Cleveland, UK.
*
Mr Frank Martin, F.R.C.S., Consultant ENT Surgeon, North Riding Infirmary, Newport Road, Middlesbrough, Cleveland TS1 5JE. Fax: 01642 231154
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Abstract

Numerous studies have postulated the possible benefit of corticosteroids on olfaction in patients with nasal/sinus disease. Twenty-nine patients with bilateral nasal polyps were included in our study using strict selection criteria to reduce other aetiologies of olfactory dysfunction. The University of Pennsylvania Smell Identification Test (UPSIT) was performed pre-operatively on the right and left nostrils separately. Following intranasal polypectomy the patients received a six-week course of beclomethasone nasal spray (Beconase) to one nostril only, with the other acting as a control. The UPSIT scores were again obtained for each nostril separately. Wilcoxon Signed Rank test revealed no statistically significant difference in UPSIT scores between treated and untreated nostrils (p = 0.31; power 70 per cent; ES = 0.47). We conclude that topical beclomethasone does not improve olfaction following nasal polypectomy.

Keywords

Nasal polypsSmell
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 109 , Issue 10 , October 1995 , pp. 941 - 944
Copyright
Copyright © JLO (1984) Limited 1995

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