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Dual-probe 24-hour ambulatory pH monitoring for diagnosis of laryngopharyngeal reflux

Published online by Cambridge University Press:  08 March 2006

W.J. Issing ,
P.D. Karkos ,
K. Perreas ,
C. Folwaczny  and
O. Reichel
W.J. Issing
Affiliation:
Department of Otolaryngology, The Freeman Hospital, Newcastle Upon Tyne, UK.
P.D. Karkos
Affiliation:
Department of Otolaryngology, The Freeman Hospital, Newcastle Upon Tyne, UK.
K. Perreas
Affiliation:
Department of Cardiac Surgery, Onassis Cardiac Centre, Athens, Greece.
C. Folwaczny
Affiliation:
Chirurgische Klinik der Ludwig-Maximilians-Universität München, Klinikum Innenstadt, München, Germany.
O. Reichel
Affiliation:
Klinik für Hals-, Nasen- und Ohrenkranke der Ludwig-Maximilians-Universität München, München, Germany.
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Abstract

Background: Patients with gastroesophageal reflux disease may suffer from a variety of symptoms from the upper aerodigestive tract. The objective of this study was to determine the impact of dual-probe 24-hr pH monitoring in the diagnosis of reflux-related otolaryngological disorders.

Methods: Twenty-two patients with symptoms such as chronic cough, globus pharyngeus, heartburn,dysphonia and burning sensation of the tongue underwent a complete ear, nose and throat examination, 24-hr dual-probe pH monitoring, and oesophago-gastro-duodenoscopy.

Results: pH monitoring revealed gastroesophageal (distal) reflux in all patients and pharyngeal (proximal) reflux in 21 patients. Treatment consisted of a proton pump inhibitor (esomeprazole). Within 4 weeks 68 per cent of patients had no laryngopharyngeal symptoms; within 8 weeks 95 per cent of patients were symptom-free.

Conclusions: Patients with atypical reflux symptoms such as hoarseness, globus sensation or throat-clearing responded well to anti-reflux treatment.

Keywords

Gastroesophageal RefluxLarynxDiagnosisEndoscopyMonitoring Ambulatory
Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 118 , Issue 11 , November 2004 , pp. 845 - 848
Copyright
© 2004 Royal Society of Medicine Press

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