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Dual infection with atypical mycobacteria and Mycobacterium tuberculosis causing cervical lymphadenopathy in a child

Published online by Cambridge University Press:  08 March 2006

S. Ganesan
Affiliation:
Department of Otolaryngology, Royal National Throat, Nose and Ear Hospital, Gray’s Inn Road, London
A. Thirlwall
Affiliation:
Department of Otolaryngology, Royal National Throat, Nose and Ear Hospital, Gray’s Inn Road, London
C. Brewis
Affiliation:
Department of Otolaryngology, Royal National Throat, Nose and Ear Hospital, Gray’s Inn Road, London
H. R. Grant
Affiliation:
Department of Otolaryngology, Royal National Throat, Nose and Ear Hospital, Gray’s Inn Road, London
V. M. Novelli
Affiliation:
Department of Infectious Diseases, Great Ormond Street Hospital for Children NHS Trust London, UK.

Abstract

The most common presentation of mycobacterial infection encountered in otolaryngological practice is cervical lymphadenitis. We report a child with an unusual cause of cervical lymphadenopathy, i.e. dual tuberculous infections. This had clinical ramifications as, initially Mycobacterium avium-intracellulare was grown in culture and was resistant to standard anti-tuberculous agents, and hence treated with excision of the lymph node. However, the cultures from the excised lymph node grew out Mycobacterium tuberculosis that was sensitive to standard anti-tuberculous drugs. To our knowledge, no such presentation has been reported previously. We also review the literature on cervical lymphadenitis due to atypical mycobacteria and Mycobacterium tuberculosis , with particular emphasis on clinical presentation, diagnosis and management.

Type
Research Article
Copyright
Royal Society of Medicine Press Limited 2000

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