Hostname: page-component-669899f699-8p65j Total loading time: 0 Render date: 2025-04-25T21:47:52.638Z Has data issue: false hasContentIssue false
  • English
  • Français

Detection of hepatitis B virus in the cerumen of patients with chronic hepatitis B infection

Published online by Cambridge University Press:  17 October 2013

A Eftekharian ,
H Moghaddasi ,
L Gachkar  and
S S A Amlashi
A Eftekharian*
Affiliation:
Department of Otorhinolaryngology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
H Moghaddasi
Affiliation:
Department of Otorhinolaryngology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
L Gachkar
Affiliation:
Department of Infectious Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran
S S A Amlashi
Affiliation:
Department of Otorhinolaryngology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
*
Address for correspondence: Dr A Eftekharian, Department of Otorhinolaryngology, Loghman Hospital, Kamali Ave, Kargar, 13336-31151 Tehran, Iran Fax: +98,-21-55416170 E-mail: alishko@gmail.com
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective:

To investigate hepatitis B virus DNA in the cerumen of hepatitis B virus infected patients.

Methods:

This study comprised 30 confirmed cases of chronic hepatitis B. Patients' serum samples were examined for hepatitis B surface antigen and antibodies using enzyme immunoassay systems. The presence of hepatitis B virus DNA in cerumen was investigated using a polymerase chain reaction test.

Results:

All of the samples were positive for hepatitis B surface antigen and negative for hepatitis B surface antibodies. Hepatitis virus DNA was detected in two cerumen samples (6.6 per cent of patients).

Conclusion:

Cerumen can be a potential source of transmission of hepatitis B virus.

Keywords

Hepatitis B VirusCerumenChronic Hepatitis
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 127 , Issue 11 , November 2013 , pp. 1065 - 1066
Copyright
Copyright © JLO (1984) Limited 2013 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

1Allain, JP, Candotti, D. Hepatitis B virus in transfusion medicine: still a problem? Biologicals 2012;40:180–6CrossRefGoogle ScholarPubMed
2Rimšelienė, G, Nilsen, Ø, Kløvstad, H, Blystad, H, Aavitsland, P. Epidemiology of acute and chronic hepatitis B virus infection in Norway, 1992–2009. BMC Infect Dis 2011;11:153CrossRefGoogle ScholarPubMed
3Hou, J, Liu, Z, Gu, F. Epidemiology and prevention of hepatitis B virus infection. Int J Med Sci 2005;2:50–7CrossRefGoogle ScholarPubMed
4Kwon, SY, Lee, CH. Epidemiology and prevention of hepatitis B virus infection. Korean J Hepatol 2011;17:87–95CrossRefGoogle ScholarPubMed
5Goh, EK, Son, BH, Kong, SK, Chon, KM, Cho, KS. Analysis of hepatitis B virus in the cerumen and otorrhea of chronic HBV-infected patients: is there a hepatitis B virus infectivity? Otol Neurotol 2008;29:929–32CrossRefGoogle Scholar
6Lavanchy, D. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. J Viral Hepat 2004;11:97–107CrossRefGoogle ScholarPubMed
7Ocana, S, Casas, ML, Buhigas, I, Lledo, JL. Diagnostic strategy for occult hepatitis B virus infection. World J Gastroenterol 2011;17:1553–7CrossRefGoogle ScholarPubMed
8Khan, F, Shams, S, Qureshi, ID, Israr, M, Khan, H, Sarwar, MT et al. Hepatitis B virus infection among different sex and age groups in Pakistani Punjab. Virol J 2011;8:225CrossRefGoogle ScholarPubMed
9Torbenson, M, Thomas, DL. Occult hepatitis B. Lancet Infect Dis 2002;2:479–86CrossRefGoogle ScholarPubMed
10Ott, JJ, Stevens, GA, Groeger, J, Wiersma, ST. Global epidemiology of hepatitis B virus infection: new estimates of age-specific HBsAg seroprevalence and endemicity. Vaccine 2012;30:2212–19CrossRefGoogle ScholarPubMed
11Tsai, CY, Lin, CL, Lin, SC, Liou, SW. Detection of hepatitis B virus in the aqueous humor of a hepatitis B virus carrier. Ophthalmologica 2009;223:93–5CrossRefGoogle ScholarPubMed
12Kalcioglu, MT, Durmaz, R, Ozturan, O, Bayindir, Y, Direkel, S. Does cerumen have a risk for transmission of hepatitis B? Laryngoscope 2004;114:577–80CrossRefGoogle ScholarPubMed
13Raimondo, G, Allain, JP, Brunetto, MR, Buendia, MA, Chen, DS, Colombo, M et al. Statements from the Taormina expert meeting on occult hepatitis B virus infection. J Hepatol 2008;49:652–7CrossRefGoogle ScholarPubMed