Hostname: page-component-cd9895bd7-dzt6s Total loading time: 0 Render date: 2024-12-26T17:32:07.195Z Has data issue: false hasContentIssue false
  • English
  • Français

A comparison of radiotherapy and surgery as primary treatment in the management of T3 N0 M0 glottic tumours

Published online by Cambridge University Press:  29 June 2007

D. Simpson ,
A. G. Robertson  and
D. Lamont
D. Simpson
Affiliation:
Beatson Oncology Centre, Ruchill Hospital, Glasgow
A. G. Robertson*
Affiliation:
Beatson Oncology Centre, Ruchill Hospital, Glasgow
D. Lamont
Affiliation:
West of Scotland Cancer Surveillance Unit, Ruchill Hospital, Glasgow
*
A. G. Robertson, Ph.D., F.R.C.R., F.R.C.P.(Glas.), Consultant Oncologist, Beatson Oncology Centre, Western Infirmary, Glasgow G11 6NT.
Get access Rights & Permissions [Opens in a new window]

Abstract

Seventy-four patients with Stage T3 NO MO squamous carcinoma of the glottis were treated initially by either surgery or radiotherapy between 1980 and 1985. The treatment adopted was determined by consultant preference. The long-term survival in both groups was approximately the same. Of 38 patients treated initially by radiotherapy, 25 had local recurrence. Fifteen of these underwent salvage surgery and 10 died of disease. Thirteen patients (33 per cent) retained their larynx. One of the major advantages of treating patients with stage T3 NO MO carcinoma of larynx by radiotherapy initially is that approximately one-third will retain their larynx. Local recurrences can usually be treated readily by salvage surgery.

Keywords

Laryngeal neoplasmsSurgeryRadiotherapy
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 107 , Issue 10 , October 1993 , pp. 912 - 915
Copyright
Copyright © JLO (1984) Limited 1993

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bryce, D. P. (1972) The role of surgery in the management of carcinoma of the larynx. Journal of Laryngology and Otology 86: 669–678.CrossRefGoogle ScholarPubMed
De Santo, L. W. (1984) T3 glottic cancer: options and consequences of the options. Laryngoscope 94: 1311–1315.CrossRefGoogle ScholarPubMed
Harwood, A. R., Bryce, D. P., Rider, W. D. (1980) Management of T3 glottic cancer. Clinical Otolaryngology 106: 697–699.Google ScholarPubMed
Le Roux-Robert, J. (1975) Panel discussion on glottic tumours. IV. A statistical study of 620 laryngeal carcinomas of the glottic region personally operated upon more than 5 years ago. Laryngoscope 85: 144O–1452.Google Scholar
Lundgren, J. A. V., Gilbert, R. W., van Nostrand, A. W. P., Harwood, A. R., Keane, T. G., Briant, T. D. R. (1988) T3 N0 M0 glottic carcinoma — a failure analysis. Clinical Otolaryngology 13: 455–565.CrossRefGoogle Scholar
Peto, R., Pike, M. C.Armitage, P., Breslaw, N. E., Cox, D. R., Howard, S. V., Montel, N., McPherson, K., Peto, J., Smith, P. G. (1977) Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples. British Journal of Cancer 35: 1–39.CrossRefGoogle ScholarPubMed
Stell, P. M., Dally, J. E., Singh, S. D., Ramadan, M. F., Bainton, R. (1982) The management of T3 glottic carcinoma. Clinical Otolaryngology 7: 175–180.CrossRefGoogle Scholar
UICC (1978) TNM classification of malignant tumours, 3rd Edition.Google Scholar