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A clinicopathological and immunohistochemical study of the calcifying epithelial odontogenic tumour (Pindborg tumour) in Malaysians

Published online by Cambridge University Press:  29 June 2007

K. H. Ng  and
C. H. Siar
K. H. Ng*
Affiliation:
Division of Stomatology, Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur
C. H. Siar
Affiliation:
Department of Oral Pathology, Oral Medicine, and Periodontology, Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia
*
Address for correspondence: K. H. Ng, F.D.S.R.C.P.S. (Glas.), M.R.C. Path., Division of Stomatalogy, Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur, Malaysia. Fax: 03-2938306
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Abstract

We reviewed the clinicopathological characteristics of 13 cases of calcifying epithelial odontogenic tumour (CEOT) (Pindborg tumour) diagnosed in the Division on Stomatology, Institute for Medical Research, Kuala Lumpur, over a 29-year period. There were eight female and five male patients. These consisted of eight (61.5 per cent) Malays, three (23.1 per cent) Chinese, one (7.7 per cent) Indian and one (7.7 per cent) Melanau. Their ages at presentation ranged from 19–61 years (mean age, 31.8 years). There were 12 central and one peripheral CEOT. Of these, 76.9 per cent of cases were located in the maxilla, the remaining in the mandible. The commonest clinical diagnosis was a dentigerous cyst (66.7 per cent). Enucleation was the main mode of treatment. Histologically, sheets and strands of polyhedral epithelial cells containing eosinophilic, homogeneous globules with Liesegang rings were observed. One case also showed extensive calcification and clear cell differentiation. Immunohistochemistry revealed a variable keratin staining of the CEOT epithelium, confirming its heterogeneity.

Keywords

Jaw neoplasmsOdontogenic tumours
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 110 , Issue 8 , August 1996 , pp. 757 - 762
Copyright
Copyright © JLO (1984) Limited 1996

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