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Clinical efficacy of tobramycin dexamethasone eye ointment combined with a catheter in endoscopic dacryocystorhinostomy

Published online by Cambridge University Press:  21 October 2024

Hailin Hu ,
Xiaoping Bi ,
Yimin Li ,
Junfang Wang  and
Wodong Shi Open the ORCID record for Wodong Shi [Opens in a new window]
Hailin Hu
Affiliation:
Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China
Xiaoping Bi
Affiliation:
Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China
Yimin Li
Affiliation:
Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China
Junfang Wang*
Affiliation:
Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China
Wodong Shi*
Affiliation:
Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China
*
Corresponding authors: Junfang Wang; Email: [email protected]; Wodong Shi; Email: [email protected]
Corresponding authors: Junfang Wang; Email: [email protected]; Wodong Shi; Email: [email protected]
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Abstract

Objective

To evaluate the clinical efficacy of tobramycin dexamethasone eye ointment combined with a catheter in endoscopic dacryocystorhinostomy.

Methods

Eighty chronic dacryocystitis patients were randomly divided into two groups: observation (n = 39) and control (n = 41). Both groups underwent endoscopic dacryocystorhinostomy. The observation group used tobramycin dexamethasone eye ointment and catheter support, while the control group used only the eye ointment.

Results

No statistical differences were found in gender, age, disease course or eye type. However, the anastomotic formation time and bleeding amount were significantly different between the two groups (p < 0.001). After six months of follow up, there were no significant complications differences (p > 0.05). The fluorescein disappearance test time in the observation group was significantly shorter (p < 0.001), and the clinical effective rate was significantly higher (97.4 per cent vs 78 per cent, p < 0.05) in the observation group.

Conclusion

Using tobramycin dexamethasone eye ointment combined with a catheter slightly prolongs the operation time and increases bleeding, but promotes anastomotic healing, accelerates tear drainage, improves the operation success rate and is economically efficient.

Keywords

catheterstobramycin dexamethasone eye ointmentendoscopic dacryocystorhinostomy
Type
Main Article
Information
The Journal of Laryngology & Otology , Volume 139 , Issue 1 , January 2025 , pp. 48 - 53
Copyright
Copyright © The Author(s), 2024. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED

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Footnotes

Wodong Shi takes responsibility for the integrity of the content of the paper

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