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Carcinoma ex pleomorphic adenoma of the soft palate

Published online by Cambridge University Press:  29 June 2007

Toshio Yoshihara ,
Masayo Tanaka ,
Mitsuko Itoh  and
Tetsuo Ishii
Toshio Yoshihara*
Affiliation:
Department of Otolaryngology, Tokyo Women's Medical College, Tokyo, Japan
Masayo Tanaka
Affiliation:
Department of Otolaryngology, Tokyo Women's Medical College, Tokyo, Japan
Mitsuko Itoh
Affiliation:
Department of Otolaryngology. Shiseikai Daini Hospital, Tokyo, Japan
Tetsuo Ishii
Affiliation:
Department of Otolaryngology, Tokyo Women's Medical College, Tokyo, Japan
*
Address for correspondence: Dr Toshio Yoshihara, Department of Otolaryngology, Tokyo Women's Medical College, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162, Japan
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Abstract

A case of carcinoma ex pleomorphic adenoma arising in the soft palate is reported. The tumour presented had enlarged gradually over 10 years and finally occupied the oral cavity. The patient was admitted to our hospital due to disturbance of her speech and swallowing, and a sudden haemorrhage from the tumour. The initial pathological diagnosis by open biopsy was benign pleomorphic adenoma. After total resection, histological examination revealed that the tumour was composed partly of benign pleomorphic adenoma and partly of an adenocarcinomatous component. The carcinoma cells with prominent nucleoli were spheroid or polygonal in shape, and frequently formed ductal structures with areas of necrosis. Mitoses were also found. These findings showed that this tumour was a secondary carcinoma which had developed in a preexisting pleomorphic adenoma.

Keywords

Palate, softSalivary gland neoplasmsAdenocarcinomaPleomorphic adenoma
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 109 , Issue 3 , March 1995 , pp. 240 - 243
Copyright
Copyright © JLO (1984) Limited 1995

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