Hostname: page-component-78c5997874-8bhkd Total loading time: 0 Render date: 2024-11-08T07:33:50.175Z Has data issue: false hasContentIssue false

Candida epiglottitis in an adult with acquired immunodeficiency syndrome treated with oral fluconazole

Published online by Cambridge University Press:  29 June 2007

Leslie Israel*
Affiliation:
Department of Internal Medicine, Yale University, New Haven, Connecticut.
Majid Sadigh
Affiliation:
Department of Medicine, St Mary's Hospital, Waterbury, ConnecticutUSA.
*
Address for correspondence: Dr Leslie Israel, Department of Internal Medicine, St. Mary's Hospital, 56 Franklin Street, Waterbury, Connecticut 06706, USA. Fax: 203 591-3049

Abstract

Candida epiglottitis has been reported in immunocompromised patients, but in only one paediatric patient with human immunodeficiency virus. We present possibly the first reported case of Candida infection of the epiglottis in an adult with human immunodeficiency virus treated with oral fluconazole. We review the symptoms, diagnosis. and management of the published cases of Candida epiglottitis in patients without the human immunodeficiency virus. Laryngoscopy and culture are diagnostic.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1995

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Cochran, J. H., Fee, W., Maze, A. (1979) Epiglottitis in an immunosuppressed host. Western Journal of Medicine 131: 150152.Google Scholar
Cole, S., Zwain, M., Lundgerg, B., Hoffman, J., Bailey, L., Ernstoff, M. (1987) Candida epiglottitis in an adult with acute nonlymphocytic leukemia. American Journal of Medicine 82: 662664.CrossRefGoogle Scholar
Colman, M. (1986) Epiglottitis in immunocompromised patients. Head and Neck Surgery 8: 466468.CrossRefGoogle ScholarPubMed
Cuomo, J. A., Dismukes, W. E. (1994) Oral azole drugs as systemic antifungal therapy. New England Journal of Medicine 330: 263272.Google Scholar
Devita, M., Wagner, I. (1986) Acute epiglottitis in the adult. Critical Care Medicine 14: 10821083.CrossRefGoogle ScholarPubMed
Galgiani, J. (1990) Fluconazole, a new antifungal agent. Annals of Internal Medicine 113: 177179.CrossRefGoogle ScholarPubMed
Haberman, R. S., Becker, M., Ford, C. (1983) Candida epiglottitis Archives of Otolaryngology 109: 770771.CrossRefGoogle Scholar
MayoSmith, M., Hirsch, P., Wodzinski, S., Schiffman, F. (1986) Acute epiglottitis in adults (an eight-year experience in the state of Rhode Island). New England Journal of Medicine 314: 11331139.CrossRefGoogle ScholarPubMed
Paya, C. V. (1993) Fungal infections in solid-organ transplantation. Clinical Infectious Diseases 16: 677688.Google Scholar
Rex, J. H., Bennett, J. E., Sugar, A. M., Pappas, P G., Van Der Horst, C. M., Edwards, J. F., Washburn, R. G., Scheld, W. M., Karchmer, A. W., Neu, H. C., Stern, J. J., Tuazon, C. U., Dine, A. P., Levenstein, M. J., Webb, C. D., NIAID MSG. and the Candidemia Study group. University of Texas Medical School, Houston, Texas and Roerig/Pfizer, New York City, NY. (1993)Google Scholar
Rex, J. H., Bennett, J. E., Sugar, A. M., Pappas, P G., Van Der Horst, C. M., Edwards, J. F., Washburn, R. G., Scheld, W. M., Karchmer, A. W., Neu, H. C., Stern, J. J., Tuazon, C. U., Dine, A. P., Levenstein, M. J., Webb, C. D., Fluconazole versus Amphotericin B for treatment of candidemia: results of a randomized multicenter trial. In Program and Abstracts of the 33rd Interscience Conference on Antimicrobial Agents and Chemotherapy, New Orleans. October 1720. 1993. American Society for Microbiology, Washington, D.C., Abstract 805, p 267.Google Scholar
Rothstein, S. G., Persky, M. S., Edelman, B., Gittleman, P. E., Stroschein, M. (1989) Epiglottitis in AIDS patients Laryngoscope 99: 389392.CrossRefGoogle ScholarPubMed
Tashijian, L., Peacock, J. (1984) Laryngeal candidiasis Report of seven cases and review of the literature. Archives of Otolaryngology 110: 806809.CrossRefGoogle Scholar
Walsh, T. J., Gray, W. (1987) Candida epiglottitis in immunocompromised patients. Chest 91: 482485.CrossRefGoogle ScholarPubMed
Wurtele, P. (1992) Acute epiglottitis: historical highlights and perspectives for future research. Journal of Otolaryngology (Suppl. 2): 115.Google Scholar