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Biofilms and their role in otorhinolaryngological disease

Published online by Cambridge University Press:  11 April 2008

E Macassey  and
P Dawes
E Macassey*
Affiliation:
Department of Otorhinolaryngology, Dunedin Public Hospital, New Zealand
P Dawes
Affiliation:
Department of Otorhinolaryngology, Dunedin Public Hospital, New Zealand
*
Address for correspondence: Dr Emily Macassey, Department of Otorhinolaryngology, Dunedin Public Hospital, Great King Street, Dunedin, New Zealand. Fax: 006434747956 E-mail: [email protected]
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Abstract

Objective:

To describe the pathophysiology of biofilm communities and their role in otorhinolaryngological disease, with reference to the published literature.

Design:

Review of relevant literature, using Medline and the combined search terms ‘biofilms’ and ‘otorhinolaryngology’, and also various related keywords such as ‘tonsil’ and ‘adenoid’.

Results:

Description of biofilm pathophysiology and of published reports of biofilms in otorhinolaryngological disease.

Conclusion:

Virtually all microbes live in biofilm communities. Within these communities, the microbes assume differing specialised roles which confer survival advantages on the community. These communities cause chronic and device-associated infections. Within the specialist field of otorhinolaryngology, biofilms have been shown to play a role in many infections, including: chronic otitis media, cholesteatoma, chronic tonsillitis, chronic sinusitis, and infections of tracheostomies, endotracheal tubes and cochlear implants.

Keywords

BiofilmsOtolaryngology
Type
Review Articles
Information
The Journal of Laryngology & Otology , Volume 122 , Issue 12 , December 2008 , pp. 1273 - 1278
Copyright
Copyright © JLO (1984) Limited 2008

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