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Association of epicardial fat thickness with clinical and polysomnographic parameters in non-obese obstructive sleep apnoea patients

Published online by Cambridge University Press:  23 April 2018

S Derin ,
I Altun ,
S Koseoglu ,
C Sahin ,
M Yilmaz ,
F Akin  and
M Sahan
S Derin*
Affiliation:
Department of Otorhinolaryngology, School of Medicine, Muğla Sıtkı Koçman University, Muğla, Turkey
I Altun
Affiliation:
Department of Cardiology, School of Medicine, Muğla Sıtkı Koçman University, Muğla, Turkey
S Koseoglu
Affiliation:
Department of Otorhinolaryngology, School of Medicine, Muğla Sıtkı Koçman University, Muğla, Turkey
C Sahin
Affiliation:
Department of Internal Medicine, School of Medicine, Muğla Sıtkı Koçman University, Muğla, Turkey
M Yilmaz
Affiliation:
Department of Neurology, School of Medicine, Muğla Sıtkı Koçman University, Muğla, Turkey
F Akin
Affiliation:
Department of Cardiology, School of Medicine, Muğla Sıtkı Koçman University, Muğla, Turkey
M Sahan
Affiliation:
Department of Otorhinolaryngology, School of Medicine, Muğla Sıtkı Koçman University, Muğla, Turkey
*
Author for correspondence: Dr Serhan Derin, Tıp Fakültesi, Muğla Sıtkı Koçman Üniversitesi, Haluk Ozsoy Street, Orhaniye District, 48000 Muğla, Turkey E-mail: [email protected]
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Abstract

Objectives:

This study aimed to investigate the relationship of epicardial fat thickness with severity of obstructive sleep apnoea, and clinical and polysomnographic parameters, and to determine independent predictors for epicardial fat thickness.

Methods:

A total of 84 patients with a body mass index of less than 30 kg/m2 and suspected sleep-disordered breathing were included in the study. The correlations of epicardial fat thickness with polysomnographic and clinical data, and severity of obstructive sleep apnoea, were investigated.

Results:

Mean epicardial fat thickness was 3.75 ± 1.07 mm in the study group (n = 62) and 2.97 ± 0.62 mm in the control group (n = 22) (p < 0.001). There were significant positive correlations between epicardial fat thickness and: apnoea/hypopnoea index, oxygen desaturation index 3 and minimum oxygen saturation, as well as with age, body mass index, and neck and waist circumferences.

Conclusion:

Non-obese obstructive sleep apnoea patients have thicker epicardial fat compared to controls. Oxygen desaturation index 3 has a strong correlation with epicardial fat thickness and is an independent predictor of it.

Keywords

Visceral Adipose TissueSleep Apnea SyndromesEchocardiographyHypoxemiaObesity
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 132 , Issue 5 , May 2018 , pp. 439 - 445
Copyright
Copyright © JLO (1984) Limited 2018 

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Footnotes

Presented at the 12th National Congress of Rhinology, 21–24 April 2016, Antalya, Turkey.

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