Hostname: page-component-586b7cd67f-gb8f7 Total loading time: 0 Render date: 2024-11-24T17:08:24.425Z Has data issue: false hasContentIssue false

Adult Laryngeal Rhabdomyosarcoma: is aggressive treatment justified in all cases? A case report and review of the literature

Published online by Cambridge University Press:  01 September 2009

G X Papacharalampous
Affiliation:
First Department of Otolaryngology – Head and Neck Surgery, National and Kapodistrian University of Athens, Hippokrateion Hospital, Athens, Greece
L Manolopoulos
Affiliation:
First Department of Otolaryngology – Head and Neck Surgery, National and Kapodistrian University of Athens, Hippokrateion Hospital, Athens, Greece
S Korres
Affiliation:
First Department of Otolaryngology – Head and Neck Surgery, National and Kapodistrian University of Athens, Hippokrateion Hospital, Athens, Greece
C Dicoglou
Affiliation:
Department of Histopathology, Hippokrateion Hospital, Athens, Greece
A Bibas*
Affiliation:
First Department of Otolaryngology – Head and Neck Surgery, National and Kapodistrian University of Athens, Hippokrateion Hospital, Athens, Greece
*
Address for correspondence: Mr Athanasios Bibas, 2 Nikitara Str, 154 51 Athens, Greece. E-mail: [email protected]

Abstract

Background:

Adult laryngeal rhabdomyosarcomas are rare tumours commonly treated by laryngectomy.

Case report:

We present a case of subglottic laryngeal rhabdomyosarcoma in an elderly woman, treated by endoscopic resection.

Conclusion:

Despite the fact that this tumour is traditionally treated aggressively, this approach is not supported by the literature. Due to the varying biological behaviour of this tumour in adults, we believe that conservative surgical procedures or combination therapies should be preferred, rather than total laryngectomy.

Type
Online Only Clinical Records
Copyright
Copyright © JLO (1984) Limited 2009

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Da Mosto, MC, Marchiori, C, Rinaldo, A, Ferlito, A. Laryngeal pleomorphic rhabdomyosarcoma. A critical review of the literature. Ann Otol Rhinol Laryngol 1996;105:289–94CrossRefGoogle ScholarPubMed
2Dagher, R, Helman, L. Rhabdomyosarcoma: an overview. Oncologist 1999;4:3444Google Scholar
3Feldman, BA. Rhabdomyosarcoma of the head and neck. Laryngoscope 1982;92:424–40Google Scholar
4Masson, JK, Soule, EH. Embryonal rhabdomyosarcoma of the head and neck. Report on eighty-eight cases. Am J Surg 1965;110:585–91CrossRefGoogle ScholarPubMed
5Barnes, L, Ferlito, A. Soft tissue neoplasms. In: Ferlito, A, ed.Neoplasms of the Larynx. Edinburgh: Churchill Livingstone, 1993;265304Google Scholar
6Newton, WA Jr, Gehan, EA, Webber, BL, Marsden, HB, van Unnik, AJ, Hamoudi, AB et al. Classification of rhabdomyosarcomas and related sarcomas. Cancer 1995;76:1073–853.0.CO;2-L>CrossRefGoogle ScholarPubMed
7Dikbas, O, Altundag, K, Abali, H, Turker, A, Engin, H, Sungur, A et al. Embryonal rhabdomyosarcoma of the larynx. Otolaryngol Head Neck Surg 2005;133:160–2Google Scholar
8Filipo, D, Crifo, S. Primary muscular sarcoma of the larynx [in Italian]. Boll Mal Orecchio Gola Naso 1964;82:599627Google ScholarPubMed
9Rodriguez, LA, Ziskind, J. Rhabdomyosarcoma of larynx. Laryngoscope 1970;80:1733–9Google Scholar
10Grouls, V, Bechtelsheimer, H. Rhabdomyosarcoma in the ear, nose and throat. Case reports of three adults [in German]. Laryngol Rhinol Otol (Stuttg) 1974;53:489500Google Scholar
11Hall-Jones, J. Rhabdomyosarcoma of the larynx. J Laryngol Otol 1975;89:969–76Google Scholar
12Frugoni, P, Ferlito, A. Pleomorphic rhabdomyosarcoma of the larynx: a case report and review of the literature. J Laryngol Otol 1976;90:687–98CrossRefGoogle Scholar
13Aleksandar, A, Filipce, I, Caparevski, S, Stavrić, G. Rhabdomyosarcoma of the larynx [in Serbian]. Gotisen Zbornik na Medicinskiot Fakultet vo Skopje 1976;22:615–18Google Scholar
14Lamendola, MG, Buonocore, U. Rhabdomyosarcoma of the larynx [in Italian]. Riv Anat Patol Oncol 1977;42:111–47Google Scholar
15Marasso, A, Galietti, F, Aluffi, E, Poy, G, Gays, E.A case of rhabdomyosarcoma with double localization: laryngeal and bronchial [in Italian]. Arch Sci Med 1977;134:499503Google Scholar
16Winter, LK, Lorentzen, M. Rhabdomyosarcoma of the larynx. Report of two cases and a review of the literature. J Laryngol Otol 1978;92:417–24CrossRefGoogle Scholar
17Franz, B. A contribution to cytopathology of the pleomorphic rhabdomyosarcoma in the larynx [in German]. Laryngol Rhinol Otol (Stuttg) 1979;58:920–5Google Scholar
18Srinivasan, U, Talvalkar, GV. True carcinosarcoma of the larynx: a case report. J Laryngol Otol 1979;93:1031–5CrossRefGoogle ScholarPubMed
19Kleinsasser, O, Glanz, H. Myogenic tumours of the larynx. Arch Otorhinolaryngol 1979;225:107–19Google Scholar
20Haerr, RW, Turalba, CI, el-Mahdi, AM, Brown, KL. Alveolar rhabdomyosarcoma of the larynx: case report and literature review. Laryngoscope 1987;97:339–44CrossRefGoogle ScholarPubMed
21De Agostino, G, Coppo, GF, Fracchia, P, Roberto, C, Pavesi, M.Rhabdomyosarcoma of the larynx. Description of a case and review of the literature [in Italian]. Otorinolaringologia 1988;38:327–34Google Scholar
22Jahnke, V, Vogl, T. Non-squamous epithelial malignancies of the larynx with special reference to MRT diagnosis [in German]. Laryngorhinootologie 1994;73(1):32–5Google Scholar
23Ruske, DR, Glassford, N, Costello, S, Stewart, IA. Laryngeal rhabdomyosarcoma in adults. J Laryngol Otol 1998;112:670–2CrossRefGoogle ScholarPubMed
24Akyol, MU, Sozeri, B, Kucukali, T, Ogretmenoglu, O. Laryngeal pleomorphic rhabdomyosarcoma. Eur Arch Otorhinolaryngol 1998;255:307–10CrossRefGoogle ScholarPubMed
25Abali, H, Aksoy, S, Sungur, A, Yalcin, S. Laryngeal involvement of rhabdomyosarcoma in an adult. World J Surg Oncol 2003;1:17Google Scholar
26Knipe, TA, Chandra, RK, Bugg, MF. Sclerosing rhabdomyosarcoma: a rare variant with predilection for the head and neck. Laryngoscope 2005;115:4850CrossRefGoogle ScholarPubMed
27Ferrari, A, Dileo, P, Casanova, M, Bertulli, R, Meazza, C, Gandola, L et al. Rhabdomyosarcoma in adults. A retrospective analysis of 171 patients treated at a single institution. Cancer 2003;98:571–80CrossRefGoogle ScholarPubMed
28Little, DJ, Ballo, MT, Zagars, GK, Pisters, PW, Patel, SR, El-Naggar, AK et al. Adult rhabdomyosarcoma: outcome following multimodality treatment. Cancer 2002;95:377–88Google Scholar
29Hawkins, WG, Hoos, A, Antonescu, CR, Urist, MJ, Leung, DH, Gold, JS et al. Clinicopathologic analysis of patients with adult rhabdomyosarcoma. Cancer 2001;91:7948033.0.CO;2-Q>CrossRefGoogle ScholarPubMed
30Esnaola, NF, Rubin, BP, Baldini, EH, Vasudevan, N, Demetri, GD, Fletcher, CD et al. Response to chemotherapy and predictors of survival in adult rhabdomyosarcoma. Ann Surg 2001;234:215–23Google Scholar
31Bizer, LS. Rhabdomyosarcoma. Am J Surg 1980;140:687–91Google Scholar
32Canalis, RF, Platz, CE, Cohn, AM. Laryngeal rhabdomyosarcoma. Arch Otolaryngol 1976;102:104–7CrossRefGoogle ScholarPubMed
33Edmondson, JH. Role of adjuvant chemotherapy in the management of patients with soft tissue sarcomas. Cancer Treat Rep 1984;68:1063–6Google Scholar